2-bromocyclohexyl formate

Base Information

• Chemical Name: 2-bromocyclohexyl formate
• CAS No.: 56946-25-9
• Molecular Formula: C₇H₁₁BrO₂
• Molecular Weight: 207.067
• Mol file: 56946-25-9.mol

Synonyms:2-bromocyclohexyl formate

Chemical Property of 2-bromocyclohexyl formate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-bromocyclohexyl formate

There total 7 articles about 2-bromocyclohexyl formate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

N,N-dimethyl-formamide (68-12-2,33513-42-7) + cyclohexene (110-83-8) → 2-bromocyclohexyl formate (56946-25-9)

Guidance literature:

N,N-dimethyl-formamide; cyclohexene; With dibromamine-T; at 20 ℃; for 0.166667h; Inert atmosphere;

With water; for 0.25h;

DOI:10.1016/j.tetlet.2011.11.138

Reference yield: 50.0%

cyclohexane-1,2-epoxide (286-20-4) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → (±)-trans-2-bromocyclohexyl formate (33601-27-3,56946-25-9) + cyclohexene (110-83-8)

Guidance literature:

With bromine; triphenylphosphine; at 0 ℃; for 0.5h;

DOI:10.1016/S0040-4020(02)00699-3

Reference yield:

N,N-dimethyl-formamide (68-12-2,33513-42-7) + cyclohexene (110-83-8) → (±)-cis-2-bromocyclohexyl formate + (±)-trans-2-bromocyclohexyl formate (33601-27-3,56946-25-9)

Guidance literature:

With Oxone; ammonium bromide; at 20 ℃; for 2h; Overall yield = 70 %Chromat.; diastereoselective reaction; Green chemistry;

DOI:10.1016/j.tetlet.2014.04.103

upstream raw materials:

formic acid

bromotrinitromethane

cyclohexene

N,N-dimethyl-formamide

Downstream raw materials:

2-bromo-cyclohexanol