ethyl (2S,3R)-1-(bis(4-methoxy-3,5-dimethylphenyl)methyl)-3-(2-pyridyl)aziridine-2-carboxylate

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Chemical Name:ethyl (2S,3R)-1-(bis(4-methoxy-3,5-dimethylphenyl)methyl)-3-(2-pyridyl)aziridine-2-carboxylate
CAS No.:1606993-90-1
Molecular Formula:C₂₉H₃₄N₂O₄
Molecular Weight:474.6
Hs Code.:

Synonyms:ethyl (2S,3R)-1-(bis(4-methoxy-3,5-dimethylphenyl)methyl)-3-(2-pyridyl)aziridine-2-carboxylate

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Chemical Property of ethyl (2S,3R)-1-(bis(4-methoxy-3,5-dimethylphenyl)methyl)-3-(2-pyridyl)aziridine-2-carboxylate

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Technology Process of ethyl (2S,3R)-1-(bis(4-methoxy-3,5-dimethylphenyl)methyl)-3-(2-pyridyl)aziridine-2-carboxylate

There total 1 articles about ethyl (2S,3R)-1-(bis(4-methoxy-3,5-dimethylphenyl)methyl)-3-(2-pyridyl)aziridine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.2%

: 1121-60-4
pyridine-2-carbaldehyde

: 623-73-4
diazoacetic acid ethyl ester

: 1072879-54-9
3,3',5,5'-tetramethyl-4,4'-dimethoxy benzhydrylamine

: 1606993-90-1
ethyl (2S,3R)-1-(bis(4-methoxy-3,5-dimethylphenyl)methyl)-3-(2-pyridyl)aziridine-2-carboxylate

Guidance literature:: 3,3',5,5'-tetramethyl-4,4'-dimethoxy benzhydrylamine; With triphenylborane; (R)-t-Bu₂VANOL; In toluene; at 80 ℃; for 0.5h; Inert atmosphere; Schlenk technique;

pyridine-2-carbaldehyde; diazoacetic acid ethyl ester; In toluene; at 25 ℃; for 24h; enantioselective reaction; Molecular sieve; Inert atmosphere; Schlenk technique;
DOI:10.1002/ejoc.201301766