1,1-dimethylethyl 4-(4-chloro-2-fluorophenyl)-4-cyano-1-piperidinecarboxylate

Base Information

Chemical Name:1,1-dimethylethyl 4-(4-chloro-2-fluorophenyl)-4-cyano-1-piperidinecarboxylate
CAS No.:1093956-69-4
Molecular Formula:C₁₇H₂₀ClFN₂O₂
Molecular Weight:338.809
Hs Code.:

Synonyms:1,1-dimethylethyl 4-(4-chloro-2-fluorophenyl)-4-cyano-1-piperidinecarboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,1-dimethylethyl 4-(4-chloro-2-fluorophenyl)-4-cyano-1-piperidinecarboxylate

Chemical Property:

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Technology Process of 1,1-dimethylethyl 4-(4-chloro-2-fluorophenyl)-4-cyano-1-piperidinecarboxylate

There total 1 articles about 1,1-dimethylethyl 4-(4-chloro-2-fluorophenyl)-4-cyano-1-piperidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 75279-53-7
2-(4-chloro-2-fluoro-phenyl)acetonitrile

: 118753-70-1
N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine

: 1093956-69-4
1,1-dimethylethyl 4-(4-chloro-2-fluorophenyl)-4-cyano-1-piperidinecarboxylate

Guidance literature:: With sodium hydroxide; methyl tributylammonium chloride; In water; toluene; at 40 ℃; for 14h; Product distribution / selectivity;

Reference yield:

: 1093956-69-4
1,1-dimethylethyl 4-(4-chloro-2-fluorophenyl)-4-cyano-1-piperidinecarboxylate

: 1228538-16-6
4-(4-chloro-2-fluorophenyl)-4-piperidinecarbonitrile hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 23 - 45 ℃; for 1h;

Reference yield:

: 1093956-69-4
1,1-dimethylethyl 4-(4-chloro-2-fluorophenyl)-4-cyano-1-piperidinecarboxylate

: 1150315-75-5
4-(4-chloro-2-fluorophenyl)-4-piperidinecarboxylic acid

Guidance literature:: 1,1-dimethylethyl 4-(4-chloro-2-fluorophenyl)-4-cyano-1-piperidinecarboxylate; With hydrogenchloride; In water; Heating / reflux;

With acetic acid; In water; for 48h; Heating / reflux;