Bromomethyl-((S)-1-cyclohexyl-but-3-enyloxy)-dimethyl-silane

Base Information

• Chemical Name: Bromomethyl-((S)-1-cyclohexyl-but-3-enyloxy)-dimethyl-silane
• CAS No.: 130276-76-5
• Molecular Formula: C₁₃H₂₅BrOSi
• Molecular Weight: 305.33
• Mol file: 130276-76-5.mol

Synonyms:Bromomethyl-((S)-1-cyclohexyl-but-3-enyloxy)-dimethyl-silane

Chemical Property of Bromomethyl-((S)-1-cyclohexyl-but-3-enyloxy)-dimethyl-silane

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of Bromomethyl-((S)-1-cyclohexyl-but-3-enyloxy)-dimethyl-silane

There total 1 articles about Bromomethyl-((S)-1-cyclohexyl-but-3-enyloxy)-dimethyl-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

bromomethyldimethylsilyl chloride (16532-02-8) + (S)-1-cyclohexylbut-3-en-1-ol (69036-26-6,85029-11-4,94340-22-4,106756-93-8) → Bromomethyl-((S)-1-cyclohexyl-but-3-enyloxy)-dimethyl-silane (130276-76-5)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃;

DOI:10.1021/ja00178a057

Reference yield: 92.0%

Bromomethyl-((S)-1-cyclohexyl-but-3-enyloxy)-dimethyl-silane (130276-76-5) → 7-Cyclohexyl-2,2-dimethyl-[1,2]oxasilepane (130276-87-8)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tributyltin chloride; sodium cyanoborohydride; In tert-butyl alcohol; Heating;

DOI:10.1021/ja00178a057

Reference yield:

Bromomethyl-((S)-1-cyclohexyl-but-3-enyloxy)-dimethyl-silane (130276-76-5) → 1-cyclohexylpentane-1,5-diol (57740-05-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / (n-Bu)3SnCl, NaB(CN)H₃, AIBN / 2-methyl-propan-2-ol / Heating

2: 87 percent / 30percent H₂O₂, KHCO₃, / tetrahydrofuran; methanol / Heating

With 2,2'-azobis(isobutyronitrile); tributyltin chloride; dihydrogen peroxide; sodium cyanoborohydride; potassium hydrogencarbonate; In tetrahydrofuran; methanol; tert-butyl alcohol;

DOI:10.1021/ja00178a057

upstream raw materials:

bromomethyldimethylsilyl chloride

(S)-1-cyclohexylbut-3-en-1-ol

Downstream raw materials:

7-Cyclohexyl-2,2-dimethyl-[1,2]oxasilepane

1-cyclohexylpentane-1,5-diol