7-(3-Trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride

Base Information

Chemical Name:7-(3-Trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride
CAS No.:1026365-36-5
Molecular Formula:C₁₄H₇ClF₃N₃O
Molecular Weight:325.677
Hs Code.:

Synonyms:7-(3-Trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride

Suppliers and Price of 7-(3-Trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 7-(3-Trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 7-(3-Trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride

There total 5 articles about 7-(3-Trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 72851-48-0
7-(3-(trifluoromethyl)phenyl)-3-pyrazolo<1,5-a>pyrimidine carboxylic acid

: 1026365-36-5
7-(3-Trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride

Guidance literature:: With thionyl chloride; a) RT, 30 min, b) reflux, 30 min;
DOI:10.1016/0223-5234(94)90065-5

Reference yield:

: 72851-46-8
7-(α,α,α-trifluoro-m-tolyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester

: 1026365-36-5
7-(3-Trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 52 percent / 6 N aq. NaOH / ethanol / 4 h / Heating

2: SOCl₂ / a) RT, 30 min, b) reflux, 30 min

With sodium hydroxide; thionyl chloride; In ethanol;
DOI:10.1016/0223-5234(94)90065-5

Reference yield:

: 72851-19-5
(E)-3-(dimethylamino)-1-(3-(trifluoromethyl)phenyl)prop-2-en-1-one

: 1026365-36-5
7-(3-Trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / AcOH / 8 h / Heating

2: 52 percent / 6 N aq. NaOH / ethanol / 4 h / Heating

3: SOCl₂ / a) RT, 30 min, b) reflux, 30 min

With sodium hydroxide; thionyl chloride; acetic acid; In ethanol;
DOI:10.1016/0223-5234(94)90065-5