phenyl 5-O-(diphenylhydrazono)acetyl-2,3-O-isopropylidene-1-seleno-β-D-ribofuranoside

Base Information

• Chemical Name: phenyl 5-O-(diphenylhydrazono)acetyl-2,3-O-isopropylidene-1-seleno-β-D-ribofuranoside
• CAS No.: 220587-69-9
• Molecular Formula: C₂₈H₂₈N₂O₅Se
• Molecular Weight: 551.501
• Mol file: 220587-69-9.mol

Synonyms:phenyl 5-O-(diphenylhydrazono)acetyl-2,3-O-isopropylidene-1-seleno-β-D-ribofuranoside

Chemical Property of phenyl 5-O-(diphenylhydrazono)acetyl-2,3-O-isopropylidene-1-seleno-β-D-ribofuranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenyl 5-O-(diphenylhydrazono)acetyl-2,3-O-isopropylidene-1-seleno-β-D-ribofuranoside

There total 6 articles about phenyl 5-O-(diphenylhydrazono)acetyl-2,3-O-isopropylidene-1-seleno-β-D-ribofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(2,2-diphenylhydrazono)acetic acid (728-15-4) + phenyl 2,3-O-isopropylidene-1-seleno-β-D-ribofuranoside (220587-68-8) → phenyl 5-O-(diphenylhydrazono)acetyl-2,3-O-isopropylidene-1-seleno-β-D-ribofuranoside (220587-69-9)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; Ambient temperature;

DOI:10.1039/a608236j

Reference yield:

N,N-diphenylhydrazine hydrochloride (530-47-2,29666-92-0) → phenyl 5-O-(diphenylhydrazono)acetyl-2,3-O-isopropylidene-1-seleno-β-D-ribofuranoside (220587-69-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / H₂O / 2 h

2: 92 percent / DCC, DMAP / CH₂Cl₂ / 12 h

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; water;

DOI:10.1021/jo981435w

Reference yield:

Benzeneselenol (645-96-5) → phenyl 5-O-(diphenylhydrazono)acetyl-2,3-O-isopropylidene-1-seleno-β-D-ribofuranoside (220587-69-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 92 percent / BF₃*Et₂O

2: 91 percent / K₂CO₃ / tetrahydrofuran; methanol / 6 h

3: 92 percent / p-MeC₆H₄SO₃H*H₂O / 5 h

4: 92 percent / DCC, DMAP / CH₂Cl₂ / 12 h

With dmap; boron trifluoride diethyl etherate; potassium carbonate; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1021/jo981435w

upstream raw materials:

(2,2-diphenylhydrazono)acetic acid

phenyl 2,3-O-isopropylidene-1-seleno-β-D-ribofuranoside

N,N-diphenylhydrazine hydrochloride

Benzeneselenol