N,N-dimethylpyrrolidine-2-carboxamide

Base Information

Chemical Name:N,N-dimethylpyrrolidine-2-carboxamide
CAS No.:433980-61-1
Molecular Formula:C₇H₁₄N₂O
Molecular Weight:142.201
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80558433
Mol file:433980-61-1.mol

Synonyms:N,N-dimethylpyrrolidine-2-carboxamide;433980-61-1;N,N-Dimethylprolinamide;H-Pro-NMe;2-Pyrrolidinecarboxamide,N,N-dimethyl-(9CI);2-Pyrrolidinecarboxamide, N,N-dimethyl-;SCHEMBL255493;DTXSID80558433;MLLMAIJXIZOSFS-UHFFFAOYSA-N;HMS1759O09;N-dimethyl-2-pyrrolidine carboxamide;MFCD07852068;N,N-dimethyl-2-pyrrolidinecarboxamide;AKOS000199880;AKOS016346891;PB24597;PB29885;BS-13196;pyrrolidine-2-carboxylic acid dimethylamide;CS-0452507;EN300-24068;A820057;N,N-dimethylpyrrolidine-2-carboxamide, AldrichCPR;Z168876638

Suppliers and Price of N,N-dimethylpyrrolidine-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N,N-DIMETHYLPYRROLIDINE-2-CARBOXAMIDE 95.00%
5G
$ 1168.42

American Custom Chemicals Corporation
N,N-DIMETHYLPYRROLIDINE-2-CARBOXAMIDE 95.00%
2.5G
$ 983.88

American Custom Chemicals Corporation
N,N-DIMETHYLPYRROLIDINE-2-CARBOXAMIDE 95.00%
1G
$ 721.57

Total 2 raw suppliers

Chemical Property of N,N-dimethylpyrrolidine-2-carboxamide

Chemical Property:

PSA：32.34000
LogP:0.15540
XLogP3:-0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:142.110613074
Heavy Atom Count:10
Complexity:134

Purity/Quality:

97% ^*data from raw suppliers

N,N-DIMETHYLPYRROLIDINE-2-CARBOXAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C(=O)C1CCCN1

Technology Process of N,N-dimethylpyrrolidine-2-carboxamide

There total 13 articles about N,N-dimethylpyrrolidine-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 118916-60-2,97538-67-5
(2R,5S)-2-trichloromethyl-1-aza-3-oxabicyclo[3.3.0]octan-4-one

: 124-40-3
dimethyl amine

: 29802-22-0,433980-61-1
(S)-pyrrolidin-2-carboxylic acid dimethylamide

Guidance literature:: In ethanol; at 20 ℃; for 0.166667h;
DOI:10.1016/S0957-4166(02)00579-7

Reference yield:

: 42718-55-8
(S)-2-Dimethylcarbamoyl-pyrrolidine-1-carboxylic acid benzyl ester

: 29802-22-0,433980-61-1
(S)-pyrrolidin-2-carboxylic acid dimethylamide

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol;
DOI:10.1016/S0960-894X(03)00533-X

Reference yield:

: 1148-11-4
N-Benzyloxycarbonyl-L-proline

: 29802-22-0,433980-61-1
(S)-pyrrolidin-2-carboxylic acid dimethylamide

Guidance literature:: Multi-step reaction with 2 steps

1: EDC; HOAt / dimethylformamide

2: H₂ / Pd/C / methanol

With 1-hydroxy-7-aza-benzotriazole; hydrogen; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(03)00533-X