1,3-diphenyl-2-(tetra-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptosyl)-1,3-diphenylimidazolidine

Base Information

• Chemical Name: 1,3-diphenyl-2-(tetra-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptosyl)-1,3-diphenylimidazolidine
• CAS No.: 85230-61-1
• Molecular Formula: C₄₉H₅₀N₂O₅
• Molecular Weight: 746.946

Synonyms:1,3-diphenyl-2-(tetra-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptosyl)-1,3-diphenylimidazolidine

Chemical Property of 1,3-diphenyl-2-(tetra-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptosyl)-1,3-diphenylimidazolidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-diphenyl-2-(tetra-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptosyl)-1,3-diphenylimidazolidine

There total 3 articles about 1,3-diphenyl-2-(tetra-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptosyl)-1,3-diphenylimidazolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

N,N'-diphenylethylenediamine (150-61-8) + 1-Deoxy-2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl cyanide (113019-40-2) → 1,3-diphenyl-2-(tetra-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptosyl)-1,3-diphenylimidazolidine (85230-61-1)

Guidance literature:

1-Deoxy-2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl cyanide; With diisobutylaluminium hydride; In dichloromethane; at -78 ℃; for 0.5h; Inert atmosphere;

With acetic acid; In dichloromethane; at -78 ℃; for 0.0833333h; Inert atmosphere;

N,N'-diphenylethylenediamine; In methanol; dichloromethane; at 20 ℃; for 16h; Inert atmosphere;

DOI:10.1016/j.carres.2011.04.019

Reference yield:

1,3-diphenyl-2-(tetra-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptosyl)imidazolidine (71420-08-1) → 1,3-diphenyl-2-(tetra-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptosyl)-1,3-diphenylimidazolidine (85230-61-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 0.02 M sodium methoxide

2: 1.) sodium hydride / 1.) DMF, 1 h; 2.) overnight

With sodium methylate; sodium hydride;

DOI:10.1016/0008-6215(83)88220-2

Reference yield:

benzyl bromide (100-39-0) + (2S,3R,4R,5R,6R)-2-(1,3-Diphenyl-imidazolidin-2-yl)-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol → 1,3-diphenyl-2-(tetra-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptosyl)-1,3-diphenylimidazolidine (85230-61-1)

Guidance literature:

With sodium hydride; Yield given. Multistep reaction; 1.) DMF, 1 h; 2.) overnight;

DOI:10.1016/0008-6215(83)88220-2

upstream raw materials:

benzyl bromide

1,3-diphenyl-2-(tetra-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptosyl)imidazolidine

N,N'-diphenylethylenediamine

1-Deoxy-2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl cyanide

Downstream raw materials:

4,5,6,8-tetra-O-acetyl-3,7-anhydro-1-deoxy-2-O-p-tolylsulfonyl-D-threo-L-talo-octitol

4,5,6,8-tetra-O-acetyl-3,7-anhydro-1-deoxy-2-O-p-tolylsulfonyl-D-threo-L-galacto-octitol

3,7-anhydro-4,5,6,8-tetra-O-benzyl-1-deoxy-2-deuterio-D-threo-L-galacto-octitol

3,7-anhydro-4,5,6,8-tetra-O-benzyl-1-deoxy-2-deuterio-D-threo-L-talo-octitol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 85230-61-1 1,3-diphenyl-2-(tetra-O-acetyl-2,6-anhydro-D-glycero-L-manno-heptosyl)-1,3-diphenylimidazolidine

Send

Send

Metric Ton KG G Pound L ML

Send

Send