(3S)-1-ethyl-5-oxopyrrolidine-3-carboxylic acid

Base Information

Chemical Name:(3S)-1-ethyl-5-oxopyrrolidine-3-carboxylic acid
CAS No.:428518-38-1
Molecular Formula:C₇H₁₁NO₃
Molecular Weight:157.169
Hs Code.:
DSSTox Substance ID:DTXSID60428004
Nikkaji Number:J1.723.251G
Wikidata:Q82240768
Mol file:428518-38-1.mol

Synonyms:428518-38-1;AC1OG6D7;DTXSID60428004;(S)-1-Ethyl-5-oxopyrrolidine-3-carboxylic acid;(3S)-1-Ethyl-5-oxopyrrolidine-3beta-carboxylic acid

Suppliers and Price of (3S)-1-ethyl-5-oxopyrrolidine-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3S)-1-ethyl-5-oxopyrrolidine-3-carboxylic acid

Chemical Property:

PSA：0.00000
LogP:0.00000
XLogP3:-0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:157.07389321
Heavy Atom Count:11
Complexity:190

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCN1CC(CC1=O)C(=O)O
Isomeric SMILES:CCN1C[C@H](CC1=O)C(=O)O

Technology Process of (3S)-1-ethyl-5-oxopyrrolidine-3-carboxylic acid

There total 7 articles about (3S)-1-ethyl-5-oxopyrrolidine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 100911-29-3
methyl 1-ethyl-5-oxo-3-pyrrolidinecarboxylate

: 52743-73-4,428518-38-1
rac-1-ethyl-5-oxopyrrolidine-3-carboxyIic acid

Guidance literature:: rac-1-ethyl-5-oxopyrrolidine-3-carboxylic acid methyl ester; With water; sodium hydroxide; In tetrahydrofuran; methanol; at 0 - 20 ℃; for 0.5h;

In tetrahydrofuran; methanol; at 20 ℃; for 0.5h;

Reference yield:

: 97-65-4,25119-64-6
2-methylenesuccinic acid

: 75-04-7,85404-22-4
ethylamine

: 52743-73-4,428518-38-1
rac-1-ethyl-5-oxopyrrolidine-3-carboxyIic acid

Guidance literature:: In tetrahydrofuran; isopropyl alcohol; at 120 ℃;

Reference yield:

: 617-52-7
Dimethyl itakonate

: 52743-73-4,428518-38-1
rac-1-ethyl-5-oxopyrrolidine-3-carboxyIic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: toluene; methanol / 22 h / 100 °C / Sealed tube

2.1: sodium hydroxide; water / tetrahydrofuran; methanol / 0.5 h / 0 - 20 °C

2.2: ion exchange resin CG₅₀ / 0.5 h / 20 °C

With water; sodium hydroxide; In tetrahydrofuran; methanol; toluene;