2-(2-Fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Base Information

Chemical Name:2-(2-Fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS No.:425378-68-3
Molecular Formula:C12H15 B F N O4
Molecular Weight:267.065
Hs Code.:2931900090
European Community (EC) Number:672-946-8
DSSTox Substance ID:DTXSID20397065
Wikidata:Q82198097
Mol file:425378-68-3.mol

Synonyms:425378-68-3;2-(2-fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;2-FLUORO-5-NITROPHENYLBORONIC ACID PINACOL ESTER;2-Fluoro-5-nitrophenylboronic acid, pinacol ester;SCHEMBL2649866;(2-FLUORO-5-NITROPHENYL)BORONIC ACID PINACOL ESTER;DTXSID20397065;FXEVKZIXXGDLFW-UHFFFAOYSA-N;MFCD06409955;AKOS015920071;AKOS025243917;AB23832;DS-1163;CS-0037855;FT-0644601;EN300-7364517;A825926;J-505619;2-FLUORO-5-NITROBENZENEBORONIC ACID, PINACOL ESTER;2-(2-Fluoro-5-nitrophenyl)-4,4,5,5,-tetramethyl-[1,3,2]dioxaborolane;2-(2-fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane;2-(2-FLUORO-5-NITROPHENYL)-4,4,5,5-TETRAMETHYL-[1,3,2]-DIOXABOROLANE;2-(2-Fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane, AldrichCPR;2-(2-fluoro-5-nitro-phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;2-Fluoro-5-nitrophenylboronic Acid Pinacol Ester

Suppliers and Price of 2-(2-Fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Fluoro-5-nitrophenylboronicacid,pinacolester
500mg
$ 65.00

TRC
2-Fluoro-5-nitrophenylboronicacid,pinacolester
100mg
$ 45.00

TRC
2-Fluoro-5-nitrophenylboronicacid,pinacolester
1g
$ 75.00

Synthonix
2-(2-Fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane 96%
5g
$ 76.00

Sigma-Aldrich
2-(2-Fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane Aldrich
1g
$ 144.00

Medical Isotopes, Inc.
2-Fluoro-5-nitrophenylboronicacidpinacolester 95+%
1 g
$ 345.00

Medical Isotopes, Inc.
2-Fluoro-5-nitrophenylboronicacidpinacolester 95+%
5 g
$ 490.00

Matrix Scientific
2-Fluoro-5-nitrophenylboronic acid pinacol ester 95+%
10g
$ 857.00

Matrix Scientific
2-Fluoro-5-nitrophenylboronic acid pinacol ester 95+%
5g
$ 599.00

Matrix Scientific
2-Fluoro-5-nitrophenylboronic acid pinacol ester 95+%
1g
$ 185.00

Total 40 raw suppliers

Chemical Property of 2-(2-Fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Chemical Property:

PSA：64.28000
LogP:2.55630
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:267.1078163
Heavy Atom Count:19
Complexity:355

Purity/Quality:

98% ^*data from raw suppliers

2-Fluoro-5-nitrophenylboronicacid,pinacolester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=C(C=CC(=C2)[N+](=O)[O-])F
Uses 2-Fluoro-5-nitrophenylboronic acid, pinacol ester

Technology Process of 2-(2-Fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

There total 3 articles about 2-(2-Fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 701-45-1
2-bromo-1-fluoro-4-nitrobenzene

: 73183-34-3
bis(pinacol)diborane

: 425378-68-3
2-(2-fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

Guidance literature:: With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium acetate; dimethyl sulfoxide; In 1,4-dioxane; at 90 ℃; for 14h;
DOI:10.1021/jm051065l

Reference yield:

: 350-46-9,178603-76-4
4-Fluoronitrobenzene

: 425378-68-3
2-(2-fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / potassium sulfate; aq. sulphuric acid; sodium bromate / 3.5 h / 65 - 72 °C

2: dichloro[1,1'-bis(PHPh₂)ferrocene]palladium(II)*CH₂Cl₂; dimethyl sulfoxide / dioxane / 14 h / 90 °C

With sodium bromate; potassium sulfate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; sulfuric acid; dimethyl sulfoxide; In 1,4-dioxane;
DOI:10.1021/jm051200u

Reference yield:

: 425378-68-3
2-(2-fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,4-dioxane; at 80 ℃; Inert atmosphere;