tert-butyl 2-(4-(7-(4-amino-2-fluorophenoxy)thieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl(2-methoxyethyl)carbamate

Base Information

Chemical Name:tert-butyl 2-(4-(7-(4-amino-2-fluorophenoxy)thieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl(2-methoxyethyl)carbamate
CAS No.:1342835-76-0
Molecular Formula:C₂₆H₃₀FN₅O₄S
Molecular Weight:527.62
Hs Code.:

Synonyms:tert-butyl 2-(4-(7-(4-amino-2-fluorophenoxy)thieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl(2-methoxyethyl)carbamate

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Chemical Property of tert-butyl 2-(4-(7-(4-amino-2-fluorophenoxy)thieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl(2-methoxyethyl)carbamate

Chemical Property:

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Technology Process of tert-butyl 2-(4-(7-(4-amino-2-fluorophenoxy)thieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl(2-methoxyethyl)carbamate

There total 1 articles about tert-butyl 2-(4-(7-(4-amino-2-fluorophenoxy)thieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl(2-methoxyethyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1341216-35-0
3-fluoro-4-hydroxybenzenaminium chloride

: 1342835-73-7
tert-butyl 2-(4-(7-chlorothieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl(2-methoxyethyl)carbamate

: 1342835-76-0
tert-butyl 2-(4-(7-(4-amino-2-fluorophenoxy)thieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl(2-methoxyethyl)carbamate

Guidance literature:: With ammonium hydroxide; potassium tert-butylate; In water; 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran;

Reference yield:

: 1342835-76-0
tert-butyl 2-(4-(7-(4-amino-2-fluorophenoxy)thieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl(2-methoxyethyl)carbamate

: 1885-14-9
phenyl chloroformate

: 765-30-0
Cyclopropylamine

: 1342835-81-7
tert-butyl 2-(4-(7-(4-(3-cyclopropylureido)-2-fluorophenoxy)thieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl(2-methoxyethyl)carbamate

Guidance literature:: With pyridine; ammonium chloride; In N,N-dimethyl-formamide;

Reference yield:

: 1342835-76-0
tert-butyl 2-(4-(7-(4-amino-2-fluorophenoxy)thieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl(2-methoxyethyl)carbamate

: 1342828-30-1
1-cyclopropyl-3-(3-fluoro-4-(2-(1-(2-(2-methoxyethylamino)ethyl)-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)urea

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium chloride; pyridine / N,N-dimethyl-formamide

2: trifluoroacetic acid; ammonium hydroxide / 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran

With pyridine; ammonium hydroxide; ammonium chloride; trifluoroacetic acid; In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran; N,N-dimethyl-formamide;