{[2-(4-Methoxy-phenyl)-8-trifluoromethyl-quinoline-4-carbonyl]-methyl-amino}-acetic acid ethyl ester

Base Information

Chemical Name:{[2-(4-Methoxy-phenyl)-8-trifluoromethyl-quinoline-4-carbonyl]-methyl-amino}-acetic acid ethyl ester
CAS No.:148887-71-2
Molecular Formula:C₂₃H₂₁F₃N₂O₄
Molecular Weight:446.426
Hs Code.:

Synonyms:{[2-(4-Methoxy-phenyl)-8-trifluoromethyl-quinoline-4-carbonyl]-methyl-amino}-acetic acid ethyl ester

Suppliers and Price of {[2-(4-Methoxy-phenyl)-8-trifluoromethyl-quinoline-4-carbonyl]-methyl-amino}-acetic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of {[2-(4-Methoxy-phenyl)-8-trifluoromethyl-quinoline-4-carbonyl]-methyl-amino}-acetic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of {[2-(4-Methoxy-phenyl)-8-trifluoromethyl-quinoline-4-carbonyl]-methyl-amino}-acetic acid ethyl ester

There total 3 articles about {[2-(4-Methoxy-phenyl)-8-trifluoromethyl-quinoline-4-carbonyl]-methyl-amino}-acetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 13200-60-7
Sarcosine ethyl ester

: 18060-37-2
8-Trifluormethyl-2-(p-methoxy-phenyl)-cinchoninsaeure

: 148887-71-2
{[2-(4-Methoxy-phenyl)-8-trifluoromethyl-quinoline-4-carbonyl]-methyl-amino}-acetic acid ethyl ester

Guidance literature:: With dicyclohexyl-carbodiimide; In tetrahydrofuran; acetonitrile; for 4h; Ambient temperature;
DOI:10.1016/0223-5234(92)90032-V

Reference yield:

: 391-12-8
7-trifluoromethylisatin

: 148887-71-2
{[2-(4-Methoxy-phenyl)-8-trifluoromethyl-quinoline-4-carbonyl]-methyl-amino}-acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / 34percent KOH / ethanol / 14 h / 50 - 60 °C

2: 65 percent / N,N'-dicyclohexyl carbodiimide / tetrahydrofuran; acetonitrile / 4 h / Ambient temperature

With potassium hydroxide; dicyclohexyl-carbodiimide; In tetrahydrofuran; ethanol; acetonitrile;
DOI:10.1016/0223-5234(92)90032-V

Reference yield:

: 100-06-1
1-(4-methoxyphenyl)ethanone

: 148887-71-2
{[2-(4-Methoxy-phenyl)-8-trifluoromethyl-quinoline-4-carbonyl]-methyl-amino}-acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / 34percent KOH / ethanol / 14 h / 50 - 60 °C

2: 65 percent / N,N'-dicyclohexyl carbodiimide / tetrahydrofuran; acetonitrile / 4 h / Ambient temperature

With potassium hydroxide; dicyclohexyl-carbodiimide; In tetrahydrofuran; ethanol; acetonitrile;
DOI:10.1016/0223-5234(92)90032-V