4-(3-methyl-2-butenyl)-3-methoxy-5-(methoxymethoxy)benzyl alcohol

Base Information

• Chemical Name: 4-(3-methyl-2-butenyl)-3-methoxy-5-(methoxymethoxy)benzyl alcohol
• CAS No.: 930766-89-5
• Molecular Formula: C₁₅H₂₂O₄
• Molecular Weight: 266.337
• Mol file: 930766-89-5.mol

Synonyms:4-(3-methyl-2-butenyl)-3-methoxy-5-(methoxymethoxy)benzyl alcohol

Chemical Property of 4-(3-methyl-2-butenyl)-3-methoxy-5-(methoxymethoxy)benzyl alcohol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(3-methyl-2-butenyl)-3-methoxy-5-(methoxymethoxy)benzyl alcohol

There total 1 articles about 4-(3-methyl-2-butenyl)-3-methoxy-5-(methoxymethoxy)benzyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

(3-Methoxy-5-methoxymethoxy-phenyl)-methanol (126809-66-3) + prenyl bromide (870-63-3) → 4-(3-methyl-2-butenyl)-3-methoxy-5-(methoxymethoxy)benzyl alcohol (930766-89-5)

Guidance literature:

(3-Methoxy-5-methoxymethoxy-phenyl)-methanol; With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; hexane; at -20 ℃; for 1h;

With copper(I) bromide dimethylsulfide complex; In tetrahydrofuran; at -20 ℃; for 1h;

prenyl bromide; In tetrahydrofuran; at -20 ℃; for 2h;

DOI:10.1016/j.bmcl.2006.11.096

Reference yield:

4-(3-methyl-2-butenyl)-3-methoxy-5-(methoxymethoxy)benzyl alcohol (930766-89-5) + methanesulfonyl chloride (124-63-0) → methanesulfonic acid 3-methoxy-5-methoxymethoxy-4-(3-methyl-but-2-enyl)-benzyl ester

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 21.5h;

DOI:10.1016/j.bmcl.2006.11.096

Reference yield:

4-(3-methyl-2-butenyl)-3-methoxy-5-(methoxymethoxy)benzyl alcohol (930766-89-5) → 5-iodomethyl-1-methoxy-3-methoxymethoxy-2-(3-methyl-but-2-enyl)-benzene

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / CH₂Cl₂ / 21.5 h / 0 - 20 °C

2: sodium iodide / acetone / 22 h

With triethylamine; sodium iodide; In dichloromethane; acetone;

DOI:10.1016/j.bmcl.2006.11.096

upstream raw materials:

(3-Methoxy-5-methoxymethoxy-phenyl)-methanol

prenyl bromide

Downstream raw materials:

diethyl (4-(3-methyl-2-butenyl)-3-methoxy-5-(methoxymethoxy)benzyl)phosphonate

(S,S,S)-bis(methoxymethoxy)-3'-O-methylschweinfurthin

(R,R,R)-bis(methoxymethoxy)-3'-O-methylschweinfurthin F