1,3-dimethyl-5-(4-nitrobenzyl)pyrimidine-2,4,6(1H,3H,5H)-trione

Base Information

• Chemical Name: 1,3-dimethyl-5-(4-nitrobenzyl)pyrimidine-2,4,6(1H,3H,5H)-trione
• CAS No.: 114656-98-3
• Molecular Formula: C₁₃H₁₃N₃O₅
• Molecular Weight: 291.263
• Mol file: 114656-98-3.mol

Synonyms:1,3-dimethyl-5-(4-nitrobenzyl)pyrimidine-2,4,6(1H,3H,5H)-trione

Chemical Property of 1,3-dimethyl-5-(4-nitrobenzyl)pyrimidine-2,4,6(1H,3H,5H)-trione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-dimethyl-5-(4-nitrobenzyl)pyrimidine-2,4,6(1H,3H,5H)-trione

There total 7 articles about 1,3-dimethyl-5-(4-nitrobenzyl)pyrimidine-2,4,6(1H,3H,5H)-trione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

5-(4-nitrobenzylidene)-1,3-dimethylbarbituric acid (57270-89-0) → 1,3-dimethyl-5-(4-nitrobenzyl)pyrimidine-2,4,6(1H,3H,5H)-trione (114656-98-3)

Guidance literature:

With sodium tetrahydroborate; In methanol; Ambient temperature;

DOI:10.1016/S0040-4039(00)95570-9

Reference yield: 92.0%

1,3-dimethylbarbituric acid (769-42-6) + 4-nitrobenzyl chloride (619-73-8) → 1,3-dimethyl-5-(4-nitrobenzyl)pyrimidine-2,4,6(1H,3H,5H)-trione (114656-98-3)

Guidance literature:

With C₉H₁₄B₁₀ClFeNS; In toluene; at 20 ℃; for 4h;

Reference yield: 80.0%

1,3-dimethyl-5-(4'-nitrobenzyl)-5-phenylthiobarbituric acid (114657-00-0) + phenylmethanethiol (100-53-8) → phenyl phenylmethyl disulfide (16601-17-5) + 1,3-dimethyl-5-(4-nitrobenzyl)pyrimidine-2,4,6(1H,3H,5H)-trione (114656-98-3)

Guidance literature:

With triethylamine; In dichloromethane; Ambient temperature;

DOI:10.1016/S0040-4020(01)85957-3

upstream raw materials:

n-butanethiol

1,3-dimethyl-5-(4'-nitrobenzyl)-5-phenylthiobarbituric acid

5-(4-nitrobenzylidene)-1,3-dimethylbarbituric acid

phenylmethanethiol

Downstream raw materials:

5-chloro-1,3-dimethyl-5-(4'-nitrobenzyl)barbituric acid

5-hydroxy-5-(4'-nitrobenzyl)-1,3-dimethylbarbituric acid

1,3-dimethyl-5-(4'-nitrobenzyl)-5-phenylthiobarbituric acid

C₁₉H₂₃N₅O₉