(R)-(4-phenylphenoxy)methyl-3-(2-phenylethyl)-3-[(4-phenylphenoxy)methoxy]hexanoate

Base Information

Chemical Name:(R)-(4-phenylphenoxy)methyl-3-(2-phenylethyl)-3-[(4-phenylphenoxy)methoxy]hexanoate
CAS No.:215317-08-1
Molecular Formula:C₄₀H₄₀O₅
Molecular Weight:600.755
Hs Code.:

Synonyms:(R)-(4-phenylphenoxy)methyl-3-(2-phenylethyl)-3-[(4-phenylphenoxy)methoxy]hexanoate

Suppliers and Price of (R)-(4-phenylphenoxy)methyl-3-(2-phenylethyl)-3-[(4-phenylphenoxy)methoxy]hexanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (R)-(4-phenylphenoxy)methyl-3-(2-phenylethyl)-3-[(4-phenylphenoxy)methoxy]hexanoate

Chemical Property:

Purity/Quality:: 98% HPLC ^*data from raw suppliers

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Technology Process of (R)-(4-phenylphenoxy)methyl-3-(2-phenylethyl)-3-[(4-phenylphenoxy)methoxy]hexanoate

There total 4 articles about (R)-(4-phenylphenoxy)methyl-3-(2-phenylethyl)-3-[(4-phenylphenoxy)methoxy]hexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.6%

: 215317-03-6
4-(chloromethoxy)biphenyl

: 215316-59-9
(R)-3-hydroxy-3-(2-phenylethyl)-hexanoic acid

: 215317-08-1
(R)-(4-phenylphenoxy)methyl-3-(2-phenylethyl)-3-[(4-phenylphenoxy)methoxy]hexanoate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In toluene; at 110 - 117 ℃; for 5h;
DOI:10.1021/jo9809229

Reference yield:

: 92-69-3
4-Phenylphenol

: 215317-08-1
(R)-(4-phenylphenoxy)methyl-3-(2-phenylethyl)-3-[(4-phenylphenoxy)methoxy]hexanoate

Guidance literature:: Multi-step reaction with 3 steps

1: 83.2 percent / t-BuOK / dimethylformamide; tetrahydrofuran / 0.5 h / 80 °C

2: 89 percent / SOCl₂ / CH₂Cl₂ / 0.18 h / 20 °C

3: 72.6 percent / DIPEA / toluene / 5 h / 110 - 117 °C

With thionyl chloride; potassium tert-butylate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jo9809229

Reference yield:

: 215316-99-7
4-(4-Chloro-phenylsulfanylmethoxy)-biphenyl

: 215317-08-1
(R)-(4-phenylphenoxy)methyl-3-(2-phenylethyl)-3-[(4-phenylphenoxy)methoxy]hexanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / SOCl₂ / CH₂Cl₂ / 0.18 h / 20 °C

2: 72.6 percent / DIPEA / toluene / 5 h / 110 - 117 °C

With thionyl chloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; toluene;
DOI:10.1021/jo9809229