4-Isopropoxy-N-methylaniline

Base Information

Chemical Name:4-Isopropoxy-N-methylaniline
CAS No.:412292-91-2
Molecular Formula:C₁₀H₁₅NO
Molecular Weight:165.235
Hs Code.:
DSSTox Substance ID:DTXSID80592413
Wikidata:Q82486515
Mol file:412292-91-2.mol

Synonyms:4-Isopropoxy-N-methylaniline;412292-91-2;SCHEMBL2095043;DTXSID80592413;HLKXEQAYKCBPNT-UHFFFAOYSA-N;(4-isopropoxy-phenyl)-methyl-amine;N-Methyl-4-[(propan-2-yl)oxy]aniline

Suppliers and Price of 4-Isopropoxy-N-methylaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of 4-Isopropoxy-N-methylaniline

Chemical Property:

PSA：21.26000
LogP:2.58850
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:165.115364102
Heavy Atom Count:12
Complexity:117

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)OC1=CC=C(C=C1)NC

Technology Process of 4-Isopropoxy-N-methylaniline

There total 3 articles about 4-Isopropoxy-N-methylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: tert-butyl (4-isopropoxyphenyl)carbamate

: 74-88-4
methyl iodide

: 412292-91-2
4-isopropoxy-N-methylaniline

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 20h;

Reference yield:

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 7664-66-6
4-(isopropoxy)aniline

: 412292-91-2
4-isopropoxy-N-methylaniline

Guidance literature:: formaldehyd; 4-(isopropoxy)aniline; In dichloromethane; for 12h;

With sodium tetrahydroborate; In dichloromethane; at 20 ℃;
DOI:10.1016/j.bmcl.2021.127923

Reference yield:

: 7664-66-6
4-(isopropoxy)aniline

: 412292-91-2
4-isopropoxy-N-methylaniline

Guidance literature:: Multi-step reaction with 2 steps

1: dmap / dichloromethane / 20 h / 0 - 20 °C

2: sodium hydride / N,N-dimethyl-formamide / 20 h / 0 - 20 °C

With dmap; sodium hydride; In dichloromethane; N,N-dimethyl-formamide;