4-(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)benzene-1,2-diamine

Base Information

Chemical Name:4-(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)benzene-1,2-diamine
CAS No.:1137671-57-8
Molecular Formula:C₁₅H₁₄N₄O₂
Molecular Weight:282.302
Hs Code.:

Synonyms:4-(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)benzene-1,2-diamine

Suppliers and Price of 4-(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)benzene-1,2-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-[5-(4-Methoxy-phenyl)-[1,3,4]oxadiazol-2-yl]-benzene-1,2-diamine
10mg
$ 45.00

AK Scientific
4-[5-(4-Methoxy-phenyl)-[1,3,4]oxadiazol-2-yl]-benzene-1,2-diamine
100mg
$ 300.00

AK Scientific
4-[5-(4-Methoxy-phenyl)-[1,3,4]oxadiazol-2-yl]-benzene-1,2-diamine
250mg
$ 120.00

Total 2 raw suppliers

Chemical Property of 4-(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)benzene-1,2-diamine

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

4-[5-(4-Methoxy-phenyl)-[1,3,4]oxadiazol-2-yl]-benzene-1,2-diamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)benzene-1,2-diamine

There total 4 articles about 4-(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)benzene-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1137671-56-7
4-(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)-2-nitroaniline

: 1137671-57-8
4-(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)benzene-1,2-diamine

Guidance literature:: With hydrogen; platinum(IV) oxide; In tetrahydrofuran; ethanol; for 2 - 4h; under 760.051 Torr;

Reference yield:

: 1137671-55-6
4-amino-N′-(4-methoxybenzoyl)-3-nitrobenzohydrazide

: 1137671-57-8
4-(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)benzene-1,2-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: Burgess Reagent / tetrahydrofuran / 0.33 h / 150 °C / Microwave irradiation

2: hydrogen; platinum(IV) oxide / ethanol; ethyl acetate / 72 h / 20 °C / 760.05 Torr

With platinum(IV) oxide; Burgess Reagent; hydrogen; In tetrahydrofuran; ethanol; ethyl acetate;
DOI:10.1021/acs.jmedchem.7b00173

Reference yield:

: 1588-83-6
4-amino-3-nitrobenzoic acid

: 1137671-57-8
4-(5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)benzene-1,2-diamine

Guidance literature:: Multi-step reaction with 3 steps

1.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0.17 h / 20 °C

1.2: 3 h / 20 °C

2.1: Burgess Reagent / tetrahydrofuran / 0.33 h / 150 °C / Microwave irradiation

3.1: hydrogen; platinum(IV) oxide / ethanol; ethyl acetate / 72 h / 20 °C / 760.05 Torr

With platinum(IV) oxide; Burgess Reagent; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; ethanol; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.7b00173