allyl (S)-3-(allyl(benzyl)amino)-3-((3aR,5R,6S,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)propanoate

Base Information

• Chemical Name: allyl (S)-3-(allyl(benzyl)amino)-3-((3aR,5R,6S,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)propanoate
• CAS No.: 1258407-50-9
• Molecular Formula: C₂₄H₃₃NO₆
• Molecular Weight: 431.529
• Mol file: 1258407-50-9.mol

Synonyms:allyl (S)-3-(allyl(benzyl)amino)-3-((3aR,5R,6S,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)propanoate

Chemical Property of allyl (S)-3-(allyl(benzyl)amino)-3-((3aR,5R,6S,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)propanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of allyl (S)-3-(allyl(benzyl)amino)-3-((3aR,5R,6S,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)propanoate

There total 1 articles about allyl (S)-3-(allyl(benzyl)amino)-3-((3aR,5R,6S,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

3-chloroprop-1-ene (107-05-1) + 5-benzylamino-5,6-dideoxy-3-O-methyl-1,2-O-isopropylidene-β-L-ido-heptofuranuronic acid → allyl (S)-3-(allyl(benzyl)amino)-3-((3aR,5R,6S,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)propanoate (1258407-50-9)

Guidance literature:

With tris(acetonitrile)pentamethylcyclopentadienylruthenium(II) hexafluorophosphate; caesium carbonate; In dichloromethane; at 20 ℃; for 16h; Inert atmosphere;

DOI:10.1002/ejoc.201000923

Reference yield: 49.0%

allyl (S)-3-(allyl(benzyl)amino)-3-((3aR,5R,6S,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)propanoate (1258407-50-9) → (S,Z)-5-benzyl-4-((3aR,5R,6S,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)-3,4,5,6-tetrahydro-1,5-oxazonin-2(9H)-one (1258407-53-2)

Guidance literature:

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In toluene; at 80 ℃; for 20h; Inert atmosphere;

DOI:10.1002/ejoc.201000923

upstream raw materials:

3-chloroprop-1-ene

Downstream raw materials:

(S,Z)-5-benzyl-4-((3aR,5R,6S,6aR)-6-methoxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)-3,4,5,6-tetrahydro-1,5-oxazonin-2(9H)-one