Technology Process of α-phenylselenoacrylic acid
There total 4 articles about α-phenylselenoacrylic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-(Phenylseleno)-2-propensaeure-methylester;
With
potassium hydroxide;
In
water;
at 25 ℃;
With
hydrogenchloride;
In
water;
pH=2 - 3;
DOI:10.1021/jo901628a
- Guidance literature:
-
Multi-step reaction with 3 steps
1: Br2 / tetrahydrofuran
2: 1.) Mg / 1.) THF, reflux, 20 min, 2.) 45 min
3: 1.) LDA / 1.) THF, hexane, -78 deg C, 2h, 2.) -78 deg C, 10 min
With
bromine; magnesium; lithium diisopropyl amide;
In
tetrahydrofuran;
DOI:10.1021/jo00326a035
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) Mg / 1.) THF, reflux, 20 min, 2.) 45 min
2: 1.) LDA / 1.) THF, hexane, -78 deg C, 2h, 2.) -78 deg C, 10 min
With
magnesium; lithium diisopropyl amide;
DOI:10.1021/jo00326a035
