C₂₈H₄₆N₄O₂

Base Information

• Chemical Name: C₂₈H₄₆N₄O₂
• CAS No.: 75813-16-0
• Molecular Formula: C₂₈H₄₆N₄O₂
• Molecular Weight: 470.699
• Mol file: 75813-16-0.mol

Synonyms:C₂₈H₄₆N₄O₂

Chemical Property of C₂₈H₄₆N₄O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₂₈H₄₆N₄O₂

There total 3 articles about C₂₈H₄₆N₄O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.2%

chloroform (67-66-3,8013-54-5) + N4-{3-[(3-Amino-1,3-dimethyl-butylamino)-methyl]-benzyl}-2-methyl-pentane-2,4-diamine (75813-07-9) + acetone (67-64-1) → C28H46N4O2 (75813-16-0)

Guidance literature:

With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In water; at 0 - 17 ℃;

DOI:10.1021/jo00315a020

Reference yield:

4-methyl-pent-3-en-2-one (141-79-7) → C28H46N4O2 (75813-16-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 27.4 percent / ammonium hydroxide / 4 h / 45 - 50 °C

2: 20.8 percent / mercuric chloride, aluminum / H₂O / 1.) overnight room temp., 2.) 1 h, 90 deg C

3: 12.2 percent / sodium hydroxide / benzyltriethylammonium chloride / H₂O / 0 - 17 °C

With ammonium hydroxide; sodium hydroxide; aluminium; mercury dichloride; N-benzyl-N,N,N-triethylammonium chloride; In water;

DOI:10.1021/jo00315a020

Reference yield:

4-amino-4-methylpentan-2-one (625-04-7) → C28H46N4O2 (75813-16-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 20.8 percent / mercuric chloride, aluminum / H₂O / 1.) overnight room temp., 2.) 1 h, 90 deg C

2: 12.2 percent / sodium hydroxide / benzyltriethylammonium chloride / H₂O / 0 - 17 °C

With sodium hydroxide; aluminium; mercury dichloride; N-benzyl-N,N,N-triethylammonium chloride; In water;

DOI:10.1021/jo00315a020

upstream raw materials:

chloroform

N⁴-{3-[(3-Amino-1,3-dimethyl-butylamino)-methyl]-benzyl}-2-methyl-pentane-2,4-diamine

acetone

4-methyl-pent-3-en-2-one