[(S)-2-(1-Methoxy-1-methyl-ethyl)-pyrrolidin-1-yl]-phosphonic acid 2,4-dichloro-phenyl ester isopropyl ester

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Chemical Name:[(S)-2-(1-Methoxy-1-methyl-ethyl)-pyrrolidin-1-yl]-phosphonic acid 2,4-dichloro-phenyl ester isopropyl ester
CAS No.:129149-67-3
Molecular Formula:C₁₇H₂₆Cl₂NO₄P
Molecular Weight:410.278
Hs Code.:

Synonyms:[(S)-2-(1-Methoxy-1-methyl-ethyl)-pyrrolidin-1-yl]-phosphonic acid 2,4-dichloro-phenyl ester isopropyl ester

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Chemical Property of [(S)-2-(1-Methoxy-1-methyl-ethyl)-pyrrolidin-1-yl]-phosphonic acid 2,4-dichloro-phenyl ester isopropyl ester

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Technology Process of [(S)-2-(1-Methoxy-1-methyl-ethyl)-pyrrolidin-1-yl]-phosphonic acid 2,4-dichloro-phenyl ester isopropyl ester

There total 1 articles about [(S)-2-(1-Methoxy-1-methyl-ethyl)-pyrrolidin-1-yl]-phosphonic acid 2,4-dichloro-phenyl ester isopropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 683-60-3
sodium isopropylate

: 129149-60-6
[(S)-2-(1-Methoxy-1-methyl-ethyl)-pyrrolidin-1-yl]-phosphonic acid bis-(2,4-dichloro-phenyl) ester

: 129149-67-3
[(S)-2-(1-Methoxy-1-methyl-ethyl)-pyrrolidin-1-yl]-phosphonic acid 2,4-dichloro-phenyl ester isopropyl ester

Guidance literature:: In tetrahydrofuran; at 0 ℃; for 1h;
DOI:10.1021/ja00175a030

Reference yield:

: 67-56-1
methanol

: 129149-67-3
[(S)-2-(1-Methoxy-1-methyl-ethyl)-pyrrolidin-1-yl]-phosphonic acid 2,4-dichloro-phenyl ester isopropyl ester

: 129149-69-5
(R)-Phosphoric acid 2,4-dichloro-phenyl ester isopropyl ester methyl ester

: 13062-11-8,129149-69-5
(S)-Phosphoric acid 2,4-dichloro-phenyl ester isopropyl ester methyl ester

Guidance literature:: With hydrogenchloride; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;
DOI:10.1021/ja00175a030