ethyl 4-phenyl-3-methyl-2-methoxycarbonyl-2-methyl-3(Z)-butenoate

Base Information

• Chemical Name: ethyl 4-phenyl-3-methyl-2-methoxycarbonyl-2-methyl-3(Z)-butenoate
• CAS No.: 1000614-84-5
• Molecular Formula: C₁₆H₂₀O₄
• Molecular Weight: 276.332
• Mol file: 1000614-84-5.mol

Synonyms:ethyl 4-phenyl-3-methyl-2-methoxycarbonyl-2-methyl-3(Z)-butenoate

Chemical Property of ethyl 4-phenyl-3-methyl-2-methoxycarbonyl-2-methyl-3(Z)-butenoate

Chemical Property:

Purity/Quality:

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Technology Process of ethyl 4-phenyl-3-methyl-2-methoxycarbonyl-2-methyl-3(Z)-butenoate

There total 1 articles about ethyl 4-phenyl-3-methyl-2-methoxycarbonyl-2-methyl-3(Z)-butenoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-methyl-4-phenyl-2,3-butadienoate (5750-22-1) + methylmagnesium chloride (676-58-4) + methyl chloroformate (79-22-1) → ethyl 4-phenyl-3-methyl-2-methoxycarbonyl-2-methyl-3(Z)-butenoate (1000614-84-5) + ethyl 4-phenyl-3-methyl-2-methoxycarbonyl-2-methyl-3(E)-butenoate

Guidance literature:

ethyl 2-methyl-4-phenyl-2,3-butadienoate; methylmagnesium chloride; iron(III)-acetylacetonate; In tetrahydrofuran; toluene; at -78 ℃; for 1h;

methyl chloroformate; In tetrahydrofuran; toluene; at -78 - -20 ℃; Further stages. Title compound not separated from byproducts.;

DOI:10.1021/ja075750o

upstream raw materials:

ethyl 2-methyl-4-phenyl-2,3-butadienoate

methylmagnesium chloride

methyl chloroformate