S-phenyl naphthalen-2-ylcarbamothioate

Base Information

• Chemical Name: S-phenyl naphthalen-2-ylcarbamothioate
• CAS No.: 36069-79-1
• Molecular Formula: C₁₇H₁₃NOS
• Molecular Weight: 279.362
• Mol file: 36069-79-1.mol

Synonyms:S-phenyl naphthalen-2-ylcarbamothioate

Chemical Property of S-phenyl naphthalen-2-ylcarbamothioate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of S-phenyl naphthalen-2-ylcarbamothioate

There total 4 articles about S-phenyl naphthalen-2-ylcarbamothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

iodobenzene (591-50-4) + 2-napthylisocyanide (10124-78-4) → S-phenyl naphthalen-2-ylcarbamothioate (36069-79-1)

Guidance literature:

With N-methylcyclohexylamine; sulfur; 1,10-Phenanthroline; copper(II) choride dihydrate; In N,N-dimethyl-formamide; at 80 ℃; for 22h; Schlenk technique;

DOI:10.1007/s00706-020-02613-6

Reference yield: 66.0%

S-Phenyl benzenethiosulfonate (1212-08-4) + 2-napthylisocyanide (10124-78-4) → (+/-)S-isopropyl phenylsulfinate (111698-34-1,114376-03-3,126188-13-4,52736-48-8) + S-phenyl naphthalen-2-ylcarbamothioate (36069-79-1)

Guidance literature:

With sodium iodide; In isopropyl alcohol; at 30 ℃; for 4h;

DOI:10.1021/acs.orglett.6b01023

Reference yield:

diphenyldisulfane (882-33-7) → (+/-)S-isopropyl phenylsulfinate (111698-34-1,114376-03-3,126188-13-4,52736-48-8) + S-phenyl naphthalen-2-ylcarbamothioate (36069-79-1)

Guidance literature:

Multi-step reaction with 2 steps

1: N-Bromosuccinimide / acetonitrile / 24 h / 20 °C

2: sodium iodide / isopropyl alcohol / 4 h / 30 °C

With N-Bromosuccinimide; sodium iodide; In isopropyl alcohol; acetonitrile;

DOI:10.1021/acs.orglett.6b01023

upstream raw materials:

phenyl chlorothioformate

naphthalen-2-ylamine

diphenyldisulfane

S-Phenyl benzenethiosulfonate