N-(Diphenylmethyl)-N-(2-oxo-2-phenylethyl)glycine 1,1-dimethylethyl ester

Base Information

Chemical Name:N-(Diphenylmethyl)-N-(2-oxo-2-phenylethyl)glycine 1,1-dimethylethyl ester
CAS No.:158980-47-3
Molecular Formula:C₂₇H₂₉NO₃
Molecular Weight:415.532
Hs Code.:

Synonyms:N-(Diphenylmethyl)-N-(2-oxo-2-phenylethyl)glycine 1,1-dimethylethyl ester

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Chemical Property of N-(Diphenylmethyl)-N-(2-oxo-2-phenylethyl)glycine 1,1-dimethylethyl ester

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Technology Process of N-(Diphenylmethyl)-N-(2-oxo-2-phenylethyl)glycine 1,1-dimethylethyl ester

There total 3 articles about N-(Diphenylmethyl)-N-(2-oxo-2-phenylethyl)glycine 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 70-11-1
α-bromoacetophenone

: 158980-46-2
N-(Diphenylmethyl)glycine 1,1-dimethylethyl ester

: 158980-47-3
N-(Diphenylmethyl)-N-(2-oxo-2-phenylethyl)glycine 1,1-dimethylethyl ester

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In acetone; Heating;
DOI:10.1021/jo00099a050

Reference yield:

: 5292-43-3
bromoacetic acid tert-butyl ester

: 158980-47-3
N-(Diphenylmethyl)-N-(2-oxo-2-phenylethyl)glycine 1,1-dimethylethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / K₂CO₃, KI / dimethylformamide / 2 h

2: 95 percent / N,N-diisopropylethylamine / acetone / Heating

With potassium carbonate; N-ethyl-N,N-diisopropylamine; potassium iodide; In N,N-dimethyl-formamide; acetone;
DOI:10.1021/jo00099a050

Reference yield:

: 91-00-9
Benzhydrylamine

: 158980-47-3
N-(Diphenylmethyl)-N-(2-oxo-2-phenylethyl)glycine 1,1-dimethylethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / K₂CO₃, KI / dimethylformamide / 2 h

2: 95 percent / N,N-diisopropylethylamine / acetone / Heating

With potassium carbonate; N-ethyl-N,N-diisopropylamine; potassium iodide; In N,N-dimethyl-formamide; acetone;
DOI:10.1021/jo00099a050