N-[2-(3,5-difluorophenyl)-1-phenylethyl]-4,5-dihydro-1H-imidazol-2-amine formate

Base Information

Chemical Name:N-[2-(3,5-difluorophenyl)-1-phenylethyl]-4,5-dihydro-1H-imidazol-2-amine formate
CAS No.:1071783-53-3
Molecular Formula:CH₂O₂*C₁₇H₁₇F₂N₃
Molecular Weight:347.365
Hs Code.:

Synonyms:N-[2-(3,5-difluorophenyl)-1-phenylethyl]-4,5-dihydro-1H-imidazol-2-amine formate

Suppliers and Price of N-[2-(3,5-difluorophenyl)-1-phenylethyl]-4,5-dihydro-1H-imidazol-2-amine formate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[2-(3,5-difluorophenyl)-1-phenylethyl]-4,5-dihydro-1H-imidazol-2-amine formate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[2-(3,5-difluorophenyl)-1-phenylethyl]-4,5-dihydro-1H-imidazol-2-amine formate

There total 3 articles about N-[2-(3,5-difluorophenyl)-1-phenylethyl]-4,5-dihydro-1H-imidazol-2-amine formate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.0%

: 64-18-6
formic acid

: 1071784-12-7
2-(3,5-difluorophenyl)-1-phenylethanamine hydrochloride

: 64205-92-1
4,5-dihydro-1H-imidazole-2-sulfonic acid

: 1071783-53-3
N-[2-(3,5-difluorophenyl)-1-phenylethyl]-4,5-dihydro-1H-imidazol-2-amine formate

Guidance literature:: 2-(3,5-difluorophenyl)-1-phenylethanamine hydrochloride; 4,5-dihydro-1H-imidazole-2-sulfonic acid; With triethylamine; In isopropyl alcohol; at 140 ℃; for 0.166667h;

formic acid; In water; acetonitrile;

Reference yield:

: 105184-38-1
3,5-difluorophenyl acetic acid

: 1071783-53-3
N-[2-(3,5-difluorophenyl)-1-phenylethyl]-4,5-dihydro-1H-imidazol-2-amine formate

Guidance literature:: Multi-step reaction with 3 steps

1.1: thionyl chloride / N,N-dimethyl-formamide / dichloromethane / 2 h / 20 °C

1.2: 10 h / 20 °C

1.3: 0 °C

2.1: hydroxylamine hydrochloride; sodium acetate / methanol / 1 h / Heating / reflux

2.2: 20 °C

2.3: 0.5 h

3.1: triethylamine / isopropyl alcohol / 0.17 h / 140 °C

3.2: SunFire_.(TM). Prep C 18

With thionyl chloride; hydroxylamine hydrochloride; sodium acetate; triethylamine; N,N-dimethyl-formamide; In methanol; dichloromethane; isopropyl alcohol;

Reference yield:

: 71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1
benzene

: 1071783-53-3
N-[2-(3,5-difluorophenyl)-1-phenylethyl]-4,5-dihydro-1H-imidazol-2-amine formate

Guidance literature:: Multi-step reaction with 3 steps

1.1: thionyl chloride / N,N-dimethyl-formamide / dichloromethane / 2 h / 20 °C

1.2: 10 h / 20 °C

1.3: 0 °C

2.1: hydroxylamine hydrochloride; sodium acetate / methanol / 1 h / Heating / reflux

2.2: 20 °C

2.3: 0.5 h

3.1: triethylamine / isopropyl alcohol / 0.17 h / 140 °C

3.2: SunFire_.(TM). Prep C 18

With thionyl chloride; hydroxylamine hydrochloride; sodium acetate; triethylamine; N,N-dimethyl-formamide; In methanol; dichloromethane; isopropyl alcohol;