ethyl 2-(2-nitro-5-chloro-N-ethylbenzenesulfonamido)propanoate

Base Information

• Chemical Name: ethyl 2-(2-nitro-5-chloro-N-ethylbenzenesulfonamido)propanoate
• CAS No.: 904297-57-0
• Molecular Formula: C₁₃H₁₇ClN₂O₆S
• Molecular Weight: 364.807
• Mol file: 904297-57-0.mol

Synonyms:ethyl 2-(2-nitro-5-chloro-N-ethylbenzenesulfonamido)propanoate

Chemical Property of ethyl 2-(2-nitro-5-chloro-N-ethylbenzenesulfonamido)propanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 2-(2-nitro-5-chloro-N-ethylbenzenesulfonamido)propanoate

There total 1 articles about ethyl 2-(2-nitro-5-chloro-N-ethylbenzenesulfonamido)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

ethyl iodide (75-03-6) + 2-(5-chloro-2-nitro-benzenesulfonylamino)-propionic acid ethyl ester → ethyl 2-(2-nitro-5-chloro-N-ethylbenzenesulfonamido)propanoate (904297-57-0)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1002/jhet.5570390111

Reference yield: 82.0%

ethyl 2-(2-nitro-5-chloro-N-ethylbenzenesulfonamido)propanoate (904297-57-0) → ethyl 2-(2-amino-5-chloro-N-ethylbenzenesulfonamido)propanoate (904297-58-1)

Guidance literature:

With iron; acetic acid; at 60 ℃;

DOI:10.1002/jhet.5570390111

Reference yield:

ethyl 2-(2-nitro-5-chloro-N-ethylbenzenesulfonamido)propanoate (904297-57-0) → 2-(2-amino-5-chloro-N-ethylbenzenesulfonamido)propionic acid (904297-59-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / iron powd.; glacial acetic acid / 60 °C

2: 100 percent / aq. sodium hydroxide / ethanol; tetrahydrofuran / 20 °C

With sodium hydroxide; iron; acetic acid; In tetrahydrofuran; ethanol;

DOI:10.1002/jhet.5570390111

upstream raw materials:

ethyl iodide

Downstream raw materials:

ethyl 2-(2-amino-5-chloro-N-ethylbenzenesulfonamido)propanoate

2-(2-amino-5-chloro-N-ethylbenzenesulfonamido)propionic acid