2-benzhydryl succinic acid

Base Information

• Chemical Name: 2-benzhydryl succinic acid
• CAS No.: 47126-79-4
• Molecular Formula: C₁₇H₁₆O₄
• Molecular Weight: 284.312
• Mol file: 47126-79-4.mol

Synonyms:2-benzhydryl succinic acid

Chemical Property of 2-benzhydryl succinic acid

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-benzhydryl succinic acid

There total 11 articles about 2-benzhydryl succinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzhydrylidene-succinic acid (5693-09-4) → 2-benzhydryl succinic acid (47126-79-4)

Guidance literature:

With sodium amalgam;

Reference yield:

3-(ethoxycarbonyl)-4,4-diphenylbut-3-enoic acid (5438-22-2) → 2-benzhydryl succinic acid (47126-79-4)

Guidance literature:

With sodium hydroxide; nickel;

DOI:10.1021/ja01610a034

Reference yield:

benzophenone (119-61-9) → 2-benzhydryl succinic acid (47126-79-4)

Guidance literature:

Multi-step reaction with 3 steps

1: NaOCMe₂Et / benzene / Heating

2: H₂ / Pd-C / ethyl acetate

3: aq. NaOH / 95 °C

With sodium hydroxide; hydrogen; sodium tert-pentoxide; palladium on activated charcoal; In ethyl acetate; benzene;

upstream raw materials:

3-(ethoxycarbonyl)-4,4-diphenylbut-3-enoic acid

benzhydrylidene-succinic acid

5-oxo-2-phenyl-tetrahydro-furan-3-carboxylic acid

benzene

Downstream raw materials:

3-benzhydrylpyrrolidine-2,5-dione

Refernces