N-benzyl-N-methyl-1,1-diphenylmethanamine

Base Information

• Chemical Name: N-benzyl-N-methyl-1,1-diphenylmethanamine
• CAS No.: 75774-84-4
• Molecular Formula: C₂₁H₂₁N
• Molecular Weight: 287.404
• Mol file: 75774-84-4.mol

Synonyms:N-benzyl-N-methyl-1,1-diphenylmethanamine

Chemical Property of N-benzyl-N-methyl-1,1-diphenylmethanamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-benzyl-N-methyl-1,1-diphenylmethanamine

There total 8 articles about N-benzyl-N-methyl-1,1-diphenylmethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

(E)-1,1-diphenylpropan-2-one O-(4-(trifluoromethyl)benzoyl) Oxime + benzyl-methyl-amine (103-67-3) → N-benzyl-N-methyl-1,1-diphenylmethanamine (75774-84-4)

Guidance literature:

With fac-tris(2-phenylpyridinato-N,C₂')iridium(III); In acetonitrile; at 20 ℃; Irradiation; Inert atmosphere;

DOI:10.1002/ejoc.201901060

Reference yield:

1-phenyl-acetone (103-79-7,136675-26-8) → N-benzyl-N-methyl-1,1-diphenylmethanamine (75774-84-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: bis(dibenzylideneacetone)-palladium⁽⁰⁾; tri-tert-butyl phosphine; caesium carbonate / tetrahydrofuran; toluene / 12 h / 80 - 85 °C

2.1: hydroxylamine hydrochloride; pyridine / methanol / 5 h / Reflux

2.2: 2 h / 0 - 20 °C

3.1: fac-tris(2-phenylpyridinato-N,C₂')iridium(III) / acetonitrile / 20 °C / Irradiation; Inert atmosphere

With pyridine; fac-tris(2-phenylpyridinato-N,C₂')iridium(III); tri-tert-butyl phosphine; hydroxylamine hydrochloride; caesium carbonate; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In tetrahydrofuran; methanol; toluene; acetonitrile;

DOI:10.1002/ejoc.201901060

Reference yield:

bromobenzene (108-86-1,52753-63-6) → N-benzyl-N-methyl-1,1-diphenylmethanamine (75774-84-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: bis(dibenzylideneacetone)-palladium⁽⁰⁾; tri-tert-butyl phosphine; caesium carbonate / tetrahydrofuran; toluene / 12 h / 80 - 85 °C

2.1: hydroxylamine hydrochloride; pyridine / methanol / 5 h / Reflux

2.2: 2 h / 0 - 20 °C

3.1: fac-tris(2-phenylpyridinato-N,C₂')iridium(III) / acetonitrile / 20 °C / Irradiation; Inert atmosphere

With pyridine; fac-tris(2-phenylpyridinato-N,C₂')iridium(III); tri-tert-butyl phosphine; hydroxylamine hydrochloride; caesium carbonate; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In tetrahydrofuran; methanol; toluene; acetonitrile;

DOI:10.1002/ejoc.201901060

upstream raw materials:

formaldehyd

formic acid

N-benzylbenzhydrylamine

N-(diphenylmethyl)methylamine