(R)-2-(4'-(4-chlorobenzyloxy)-N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanoic acid

Base Information

Chemical Name:(R)-2-(4'-(4-chlorobenzyloxy)-N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanoic acid
CAS No.:1178858-87-1
Molecular Formula:C₂₇H₃₀ClNO₆S
Molecular Weight:532.057
Hs Code.:

Synonyms:(R)-2-(4'-(4-chlorobenzyloxy)-N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanoic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-2-(4'-(4-chlorobenzyloxy)-N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanoic acid

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Technology Process of (R)-2-(4'-(4-chlorobenzyloxy)-N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanoic acid

There total 1 articles about (R)-2-(4'-(4-chlorobenzyloxy)-N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 1178858-86-0
tert-butyl (R)-2-(4'-(4-chlorobenzyloxy)-N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanoate

: 1178858-87-1
(R)-2-(4'-(4-chlorobenzyloxy)-N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanoic acid

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 ℃; for 5h;
DOI:10.1021/jm900261f

Reference yield: 61.0%

: 1178858-87-1
(R)-2-(4'-(4-chlorobenzyloxy)-N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanoic acid

: 41879-39-4
O-(tert-butyldimethylsilanyl)hydroxylamine

: 1178858-88-2
C₃₃H₄₅ClN₂O₆SSi

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 - 20 ℃;
DOI:10.1021/jm900261f