(2R,E)-7-phenylhept-3-en-2-yl acetate

Base Information

• Chemical Name: (2R,E)-7-phenylhept-3-en-2-yl acetate
• CAS No.: 1374429-20-5
• Molecular Formula: C₁₅H₂₀O₂
• Molecular Weight: 232.323
• Mol file: 1374429-20-5.mol

Synonyms:(2R,E)-7-phenylhept-3-en-2-yl acetate

Chemical Property of (2R,E)-7-phenylhept-3-en-2-yl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2R,E)-7-phenylhept-3-en-2-yl acetate

There total 2 articles about (2R,E)-7-phenylhept-3-en-2-yl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

(E)-7-phenylhept-3-en-2-ol + vinyl acetate (108-05-4,9003-20-7) → (2S,E)-7-phenylhept-3-en-2-ol (1374429-37-4) + (2R,E)-7-phenylhept-3-en-2-yl acetate (1374429-20-5)

Guidance literature:

With Novozym 435; at 20 ℃; for 18h; optical yield given as %ee; Inert atmosphere; Enzymatic reaction;

DOI:10.1002/ejoc.201101318

Reference yield:

(E)-7-phenyl-3-hepten-2-one (106575-53-5) → (2R,E)-7-phenylhept-3-en-2-yl acetate (1374429-20-5)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium tetrahydroborate; cerium(III) chloride heptahydrate / methanol / 0.17 h / 20 °C / Inert atmosphere

2: Novozym 435 / 18 h / 20 °C / Inert atmosphere; Enzymatic reaction

With sodium tetrahydroborate; Novozym 435; cerium(III) chloride heptahydrate; In methanol; 1: Luche reduction;

DOI:10.1002/ejoc.201101318

Reference yield: 95.0%

(2R,E)-7-phenylhept-3-en-2-yl acetate (1374429-20-5) → (2R,E)-7-phenylhept-3-en-2-ol (1374429-38-5)

Guidance literature:

With water; sodium hydroxide; In methanol; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1002/ejoc.201101318

upstream raw materials:

vinyl acetate

(E)-7-phenyl-3-hepten-2-one

Downstream raw materials:

(2R,E)-7-phenylhept-3-en-2-ol

methyl (2R,3S,E)-2-(tert-butoxycarbonylamino)-3-(3-phenylpropyl)hex-4-enoate

benzyl (2R,3S,E)-2-(tert-butoxycarbonylamino)-3-(3-phenylpropyl)hex-4-enoate

(R)-2-[(R)-1-(tert-butoxycarbonylamino)-2-methoxy-2-oxoethyl]-5-phenylpentanoic acid