12-[3-Iodo-2-(2-methoxy-ethoxymethoxy)-5-nitro-benzyloxy]-dodecanoic acid

Base Information

Chemical Name:12-[3-Iodo-2-(2-methoxy-ethoxymethoxy)-5-nitro-benzyloxy]-dodecanoic acid
CAS No.:173912-54-4
Molecular Formula:C₂₃H₃₆INO₈
Molecular Weight:581.445
Hs Code.:

Synonyms:12-[3-Iodo-2-(2-methoxy-ethoxymethoxy)-5-nitro-benzyloxy]-dodecanoic acid

Suppliers and Price of 12-[3-Iodo-2-(2-methoxy-ethoxymethoxy)-5-nitro-benzyloxy]-dodecanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 12-[3-Iodo-2-(2-methoxy-ethoxymethoxy)-5-nitro-benzyloxy]-dodecanoic acid

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 12-[3-Iodo-2-(2-methoxy-ethoxymethoxy)-5-nitro-benzyloxy]-dodecanoic acid

There total 5 articles about 12-[3-Iodo-2-(2-methoxy-ethoxymethoxy)-5-nitro-benzyloxy]-dodecanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 173912-53-3
12-[3-Iodo-2-(2-methoxy-ethoxymethoxy)-5-nitro-benzyloxy]-dodecanoic acid ethyl ester

: 173912-54-4
12-[3-Iodo-2-(2-methoxy-ethoxymethoxy)-5-nitro-benzyloxy]-dodecanoic acid

Guidance literature:: With sodium hydroxide; In 1,2-dimethoxyethane; water; for 6h; Ambient temperature;
DOI:10.1021/jo951350k

Reference yield:

: 505-95-3
12-hydroxydodecanoic acid

: 173912-54-4
12-[3-Iodo-2-(2-methoxy-ethoxymethoxy)-5-nitro-benzyloxy]-dodecanoic acid

Guidance literature:: Multi-step reaction with 5 steps

1: 99 percent / H₂SO₄ / 4 h / Heating

2: 85 percent / Ag₂O / CH₂Cl₂ / 48 h / Ambient temperature

3: 99 percent / benzyltrimethylammonium iododichloride, NaHCO₃ / CH₂Cl₂; methanol / 19 h / Ambient temperature

4: 80 percent / i-Pr₂NEt / CH₂Cl₂ / 6 h / Ambient temperature

5: 99 percent / NaOH / 1,2-dimethoxy-ethane; H₂O / 6 h / Ambient temperature

With sodium hydroxide; sulfuric acid; sodium hydrogencarbonate; N,N,N-trimethylbenzenemethanaminium dichloroiodate; N-ethyl-N,N-diisopropylamine; silver(l) oxide; In methanol; 1,2-dimethoxyethane; dichloromethane; water;
DOI:10.1021/jo951350k

Reference yield:

: 78640-13-8
12-hydroxydodecanoic acid ethyl ester

: 173912-54-4
12-[3-Iodo-2-(2-methoxy-ethoxymethoxy)-5-nitro-benzyloxy]-dodecanoic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent / Ag₂O / CH₂Cl₂ / 48 h / Ambient temperature

2: 99 percent / benzyltrimethylammonium iododichloride, NaHCO₃ / CH₂Cl₂; methanol / 19 h / Ambient temperature

3: 80 percent / i-Pr₂NEt / CH₂Cl₂ / 6 h / Ambient temperature

4: 99 percent / NaOH / 1,2-dimethoxy-ethane; H₂O / 6 h / Ambient temperature

With sodium hydroxide; sodium hydrogencarbonate; N,N,N-trimethylbenzenemethanaminium dichloroiodate; N-ethyl-N,N-diisopropylamine; silver(l) oxide; In methanol; 1,2-dimethoxyethane; dichloromethane; water;
DOI:10.1021/jo951350k