3-AMINO-2-([(2-CHLOROPHENYL)METHYLENE]AMINO)-3-METHOXYACRYLONITRILE

Base Information

• Chemical Name: 3-AMINO-2-([(2-CHLOROPHENYL)METHYLENE]AMINO)-3-METHOXYACRYLONITRILE
• CAS No.: 126210-91-1
• Molecular Formula: C₁₁H₁₀ClN₃O
• Molecular Weight: 235.673
• Mol file: 126210-91-1.mol

Synonyms:(E)-3-Amino-2-{[1-(2-chloro-phenyl)-meth-(E)-ylidene]-amino}-3-methoxy-acrylonitrile

Chemical Property of 3-AMINO-2-([(2-CHLOROPHENYL)METHYLENE]AMINO)-3-METHOXYACRYLONITRILE

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-AMINO-2-([(2-CHLOROPHENYL)METHYLENE]AMINO)-3-METHOXYACRYLONITRILE

There total 1 articles about 3-AMINO-2-([(2-CHLOROPHENYL)METHYLENE]AMINO)-3-METHOXYACRYLONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

methanol (67-56-1) + 2-chloro-benzaldehyde (89-98-5) + 2-aminomalononitrile p-toluenesulfonate (5098-14-6) → (E)-3-Amino-2-{[1-(2-chloro-phenyl)-meth-(E)-ylidene]-amino}-3-methoxy-acrylonitrile (126210-91-1)

Guidance literature:

With sodium acetate; at 22 - 24 ℃; for 6h;

DOI:10.1021/jo00002a031 DOI:10.1055/s-1989-27364

upstream raw materials:

methanol

2-chloro-benzaldehyde

2-aminomalononitrile p-toluenesulfonate

Refernces

• 1、 Freeman, Fillmore,Kim, Darrick S. H. L.. "Preparation of (E,E)-4-Amino-1-aryl-3-cyano-4-methoxy-2-azabutadienes". . p. 698 - 699. Retrieved 2007/10/02.