hopantenic acid

Base Information

Chemical Name:hopantenic acid
CAS No.:49831-65-4
Molecular Formula:C₁₀H₁₉NO₅
Molecular Weight:233.265
Hs Code.:
Mol file:49831-65-4.mol

Synonyms:Butanoicacid, 4-[(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)amino]-, (S)-

Suppliers and Price of hopantenic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-[[(2S)-2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl]amino]butanoicAcid
10mg
$ 1320.00

TRC
4-[[(2S)-2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl]amino]butanoicAcid
1mg
$ 165.00

Total 26 raw suppliers

Chemical Property of hopantenic acid

Chemical Property:

PSA：0.00000
LogP:0.00000

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-[[(2S)-2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl]amino]butanoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 4-[[(2S)-2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl]amino]butanoic Acid, is an impurity of Dexpanthenol that acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine.

Technology Process of hopantenic acid

There total 4 articles about hopantenic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 599-04-2
(R)-Pantolacton

: 56-12-2
4-amino-n-butyric acid

: 18679-90-8,49831-65-4
hopantenic acid

Guidance literature:: 4-amino-n-butyric acid; With sodium hydroxide; In water;

(R)-Pantolacton; at 130 ℃; for 17h; Inert atmosphere;
DOI:10.1039/b811086g

Reference yield: 40.0%

: (R)-methyl-4-(2,4-dihydroxy-3,3-dimethylbutanamido)butanoate

: 18679-90-8,49831-65-4
hopantenic acid

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 2.5h; Inert atmosphere;
DOI:10.1016/j.bmc.2018.10.042

Reference yield:

: 599-04-2
(R)-Pantolacton

: 18679-90-8,49831-65-4
hopantenic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: diethylamine / dichloromethane; methanol / 0.25 h / 0 °C / Inert atmosphere

1.2: 2 h / 115 °C / Microwave irradiation; Inert atmosphere

2.1: lithium hydroxide / water; tetrahydrofuran / 2.5 h / 20 °C / Inert atmosphere

With diethylamine; lithium hydroxide; In tetrahydrofuran; methanol; dichloromethane; water;
DOI:10.1016/j.bmc.2018.10.042