2-(1-Benzylpyrrolidin-3-yl)propan-2-ol

Base Information

• Chemical Name: 2-(1-Benzylpyrrolidin-3-yl)propan-2-ol
• CAS No.: 351370-67-7
• Molecular Formula: C14H21 N O
• Molecular Weight: 219.32
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID60426005
• Mol file: 351370-67-7.mol

Synonyms:2-(1-benzylpyrrolidin-3-yl)propan-2-ol;351370-67-7;2-(1-BENZYL-PYRROLIDIN-3-YL)-PROPAN-2-OL;SCHEMBL2485710;DTXSID60426005;BESBVPBWOJMGFI-UHFFFAOYSA-N;BPA37067;FT-0759879

Chemical Property of 2-(1-Benzylpyrrolidin-3-yl)propan-2-ol

Chemical Property:

• PSA: 23.47000
• LogP: 2.21730
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 219.162314293
• Heavy Atom Count: 16
• Complexity: 221

Purity/Quality:

97% ^*data from raw suppliers

2-(1-Benzylpyrrolidin-3-yl)propan-2-ol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C1CCN(C1)CC2=CC=CC=C2)O

Technology Process of 2-(1-Benzylpyrrolidin-3-yl)propan-2-ol

There total 1 articles about 2-(1-Benzylpyrrolidin-3-yl)propan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-benzylpyrrolidine-3-carboxylic acid methyl ester (17012-21-4) + methylmagnesium bromide (75-16-1) → 2-(1-benzylpyrrolidin-3-yl)propan-2-ol (351370-67-7)

Guidance literature:

1-benzylpyrrolidine-3-carboxylic acid methyl ester; methylmagnesium bromide; In tetrahydrofuran; diethyl ether; at 0 - 20 ℃;

With ammonium chloride; In tetrahydrofuran; diethyl ether; at 0 ℃;

Reference yield:

2-(1-benzylpyrrolidin-3-yl)propan-2-ol (351370-67-7) → 2-(pyrrolidin-3-yl)propan-2-ol (351369-41-0)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In ethanol; at 20 ℃; under 2585.81 Torr;

upstream raw materials:

1-benzylpyrrolidine-3-carboxylic acid methyl ester

methylmagnesium bromide

Downstream raw materials:

2-(pyrrolidin-3-yl)propan-2-ol