1-Chlor-1-fluor-2-propanon

Base Information

• Chemical Name: 1-Chlor-1-fluor-2-propanon
• CAS No.: 3592-43-6
• Molecular Formula: C₃H₄ClFO
• Molecular Weight: 110.516
• Mol file: 3592-43-6.mol

Synonyms:1-Chlor-1-fluor-2-propanon

Chemical Property of 1-Chlor-1-fluor-2-propanon

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Chlor-1-fluor-2-propanon

There total 2 articles about 1-Chlor-1-fluor-2-propanon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trans-2,3-Dichlor-2-methyloxiran (55949-58-1,55949-59-2,78102-54-2) → 1,1-Dichloroacetone (513-88-2) + 1-Chlor-1-fluor-2-propanon (3592-43-6)

Guidance literature:

With silver tetrafluoroborate; In diethyl ether; for 5h; Yield given. Yields of byproduct given; Ambient temperature;

Reference yield:

C4H8ClFO (123359-21-7) → methylene chloride (74-87-3) + R32 (593-70-4) + 1-fluoro-2-propanone (430-51-3) + 1-Chlor-1-fluor-2-propanon (3592-43-6) + chloroacetone (78-95-5) + acetone (67-64-1)

Guidance literature:

With tetrachloromethane; at 160 ℃; Product distribution; other mono-, di-, and trihalomethyl hypochlorites or peroxy dicarbonates, other temperatures, other perhalogenated radical scavenger; relative ease of formation of the three α-fluoromethyl radicals, the nature of α-F substituent effect;

DOI:10.1021/jo00285a003

upstream raw materials:

trans-2,3-Dichlor-2-methyloxiran

C₄H₈ClFO

Refernces

• 1、 Griesbaum, Karl,Keul, Helmut,Kibar, Riza,Pfeffer, Bernd,Spraul, Manfred. "Halogen Epoxides, 3. Reactions of 2-Chloro- and 2,3-Dichlorooxiranes with Silver Tetrafluoroborate: Synthesis of α-Fluorinated Carbonyl Compounds". . p. 1858 - 1870. Retrieved 2007/10/02.