6-Methyl-1,2,3,4-tetrahydroisoquinoline

Base Information

• Chemical Name: 6-Methyl-1,2,3,4-tetrahydroisoquinoline
• CAS No.: 42923-76-2
• Molecular Formula: C10H13N
• Molecular Weight: 147.22
• Hs Code.: 2933499090
• DSSTox Substance ID: DTXSID10448297
• Mol file: 42923-76-2.mol

Synonyms:6-methyl-1,2,3,4-tetrahydroisoquinoline;42923-76-2;6-METHYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE;ISOQUINOLINE, 1,2,3,4-TETRAHYDRO-6-METHYL-;SCHEMBL1001109;DTXSID10448297;JQOUGGPGOWRLPX-UHFFFAOYSA-N;AKOS006295649;AB28729;BS-28018;CS-0309340;FT-0698412;EN300-176630;A826069;6-fluoro-6 inverted exclamation mark(R)-(trifluoromethyl)-2,3 inverted exclamation mark(R)-bipyridine

Chemical Property of 6-Methyl-1,2,3,4-tetrahydroisoquinoline

Chemical Property:

• Vapor Pressure: 0.023mmHg at 25°C
• Refractive Index: 1.54
• Boiling Point: 249.649 °C at 760 mmHg
• Flash Point: 107.944 °C
• PSA: 12.03000
• Density: 0.991 g/cm³
• LogP: 1.96950
• Storage Temp.: 2-8°C(protect from light)
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 147.104799419
• Heavy Atom Count: 11
• Complexity: 133

Purity/Quality:

97% ^*data from raw suppliers

6-Methyl-1,2,3,4-tetrahydroisoquinoline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC2=C(CNCC2)C=C1

Technology Process of 6-Methyl-1,2,3,4-tetrahydroisoquinoline

There total 15 articles about 6-Methyl-1,2,3,4-tetrahydroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

6-methylisoquinoline (42398-73-2,34528-67-1) → 6-methyl-1,2,3,4-tetrahydroisoquinoline (42923-76-2)

Guidance literature:

With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; potassium iodide; at 40 ℃; for 24h;

DOI:10.1002/chem.201201517

Reference yield: 87.0%

N,N-bis(p-methylbenzylamino)ethane dihydrobromide → 6-methyl-1,2,3,4-tetrahydroisoquinoline (42923-76-2) + para-methylbenzylamine (104-84-7)

Guidance literature:

With aluminium trichloride; In decalin; at 180 ℃; for 2h;

DOI:10.1080/00397919708004118

Reference yield: 74.0%

6-methyl-3,4-dihydro-2H-isoquinolin-1-one (1082041-78-8) → 6-methyl-1,2,3,4-tetrahydroisoquinoline (42923-76-2)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 2h; Reflux;

DOI:10.1016/j.bmc.2015.12.047

upstream raw materials:

2-benzenesulfonyl-6-methyl-1,2,3,4-tetrahydro-isoquinoline

4-methyl-benzaldehyde

N-(3-methyl-phenethyl)-glycine

N-benzenesulfonyl-N-(3-methyl-phenethyl)-glycine

Downstream raw materials:

(E)-methyl 4-(2-(3-(5-chloro-2-(1H-tetrazol-1-yl)phenyl)acryloyl)-6-methyl-1,2,3,4-tetrahydroisoquinoline-1-carboxamido)benzoate

(E)-4-(2-(3-(5-chloro-2-(1H-tetrazol-1-yl)phenyl)acryloyl)-6-methyl-1,2,3,4-tetrahydroisoquinoline-1-carboxamido)benzoic acid

2-(3-(3-chlorophenyl)propiolyl)-6-methyl-1,2,3,4-tetrahydroisoquinoline

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 42923-76-2 6-METHYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE

Send

Send

Metric Ton KG G Pound L ML

Send

Send