8-Brom-5-acetoxy-7-methoxy-flavon

Base Information

• Chemical Name: 8-Brom-5-acetoxy-7-methoxy-flavon
• CAS No.: 93869-48-8
• Molecular Formula: C₁₈H₁₃BrO₅
• Molecular Weight: 389.202
• Mol file: 93869-48-8.mol

Synonyms:8-Brom-5-acetoxy-7-methoxy-flavon

Chemical Property of 8-Brom-5-acetoxy-7-methoxy-flavon

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 8-Brom-5-acetoxy-7-methoxy-flavon

There total 2 articles about 8-Brom-5-acetoxy-7-methoxy-flavon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

tectochrysine (520-28-5) + acetic anhydride (108-24-7) → 8-Brom-5-acetoxy-7-methoxy-flavon (93869-48-8) + C18H13BrO5 (1215208-44-8)

Guidance literature:

tectochrysine; With tetra-N-butylammonium tribromide; In chloroform; at 20 ℃; for 2h;

acetic anhydride; With pyridine; at 20 ℃; for 3h;

DOI:10.1016/j.tet.2009.12.021

Reference yield:

→ 8-Brom-5-acetoxy-7-methoxy-flavon (93869-48-8)

Guidance literature:

8-Brom-5-hydroxy-7-methoxy-flavon, Acetanhydrid, Py.;

DOI:10.1021/jo01067a025

Reference yield: 80.5%

8-Brom-5-acetoxy-7-methoxy-flavon (93869-48-8) + sodium methylate (124-41-4) → 5-hydroxy-7,8-dimethoxyflavone (3570-62-5) + mosloflavone (740-33-0)

Guidance literature:

sodium methylate; With copper(I) bromide; In methanol; N,N-dimethyl-formamide; at 20 ℃; for 1h;

8-Brom-5-acetoxy-7-methoxy-flavon; In methanol; N,N-dimethyl-formamide; at 120 ℃; for 5h;

With hydrogenchloride; In methanol; water; N,N-dimethyl-formamide; at 20 ℃; Cooling;

DOI:10.1016/j.tet.2009.12.021

upstream raw materials:

tectochrysine

acetic anhydride

Downstream raw materials:

5-hydroxy-7,8-dimethoxyflavone

mosloflavone

Refernces