Diphenyl-phosphinic acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-(tert-butyl-diphenyl-silanyloxy)-tetrahydro-furan-2-ylmethoxymethyl ester

Base Information

Chemical Name:Diphenyl-phosphinic acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-(tert-butyl-diphenyl-silanyloxy)-tetrahydro-furan-2-ylmethoxymethyl ester
CAS No.:173034-00-9
Molecular Formula:C₄₆H₄₆N₅O₆PSi
Molecular Weight:823.96
Hs Code.:

Diphenyl-phosphinic acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-(tert-butyl-diphenyl-silanyloxy)-tetrahydro-furan-2-ylmethoxymethyl ester

Synonyms:Diphenyl-phosphinic acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-(tert-butyl-diphenyl-silanyloxy)-tetrahydro-furan-2-ylmethoxymethyl ester

Suppliers and Price of Diphenyl-phosphinic acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-(tert-butyl-diphenyl-silanyloxy)-tetrahydro-furan-2-ylmethoxymethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Diphenyl-phosphinic acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-(tert-butyl-diphenyl-silanyloxy)-tetrahydro-furan-2-ylmethoxymethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Diphenyl-phosphinic acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-(tert-butyl-diphenyl-silanyloxy)-tetrahydro-furan-2-ylmethoxymethyl ester

There total 2 articles about Diphenyl-phosphinic acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-(tert-butyl-diphenyl-silanyloxy)-tetrahydro-furan-2-ylmethoxymethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 1707-03-5
diphenyl-phosphinic acid

: 173033-97-1
N-{9-[(2R,4S,5R)-4-(tert-Butyl-diphenyl-silanyloxy)-5-methylsulfanylmethoxymethyl-tetrahydro-furan-2-yl]-9H-purin-6-yl}-benzamide

: 173034-00-9
Diphenyl-phosphinic acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-(tert-butyl-diphenyl-silanyloxy)-tetrahydro-furan-2-ylmethoxymethyl ester

Guidance literature:: With N-iodo-succinimide; In diethyl ether; 1,2-dichloro-ethane; Ambient temperature;
DOI:10.1016/0040-4039(95)01809-V

Reference yield:

: 111570-92-4
N⁶-benzoyl-3'-O-(tert-butyldiphenylsilyl)-2'-deoxyadenosine

: 173034-00-9
Diphenyl-phosphinic acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-(tert-butyl-diphenyl-silanyloxy)-tetrahydro-furan-2-ylmethoxymethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / Bz₂O₂

2: 63 percent / N-iodosuccinimide (NIS) / 1,2-dichloro-ethane; diethyl ether / Ambient temperature

With N-iodo-succinimide; dibenzoyl peroxide; In diethyl ether; 1,2-dichloro-ethane;
DOI:10.1016/0040-4039(95)01809-V

Reference yield: 71.0%

: 123126-01-2
3'-mercapto-5'-O-DMT-3'-deoxythymidine

: 173034-00-9
Diphenyl-phosphinic acid (2R,3S,5R)-5-(6-benzoylamino-purin-9-yl)-3-(tert-butyl-diphenyl-silanyloxy)-tetrahydro-furan-2-ylmethoxymethyl ester

: C₆₅H₆₇N₇O₁₀SSi

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In formamide; N,N-dimethyl-formamide; Ambient temperature; under N₂ or Ar;
DOI:10.1016/0040-4039(95)01809-V