S-benzilic-L-cysteic-NCA

Base Information

• Chemical Name: S-benzilic-L-cysteic-NCA
• CAS No.: 22911-82-6
• Molecular Formula: C₁₁H₁₁NO₃S
• Molecular Weight: 237.279
• Mol file: 22911-82-6.mol

Synonyms:S-benzilic-L-cysteic-NCA

Chemical Property of S-benzilic-L-cysteic-NCA

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of S-benzilic-L-cysteic-NCA

There total 7 articles about S-benzilic-L-cysteic-NCA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

bis(trichloromethyl) carbonate (32315-10-9) + S-benzyl-L-cysteine (3054-01-1,25988-62-9) → S-benzilic-L-cysteic-NCA (22911-82-6)

Guidance literature:

In tetrahydrofuran; for 12h;

Reference yield: 100.0%

oxalyl dichloride (79-37-8) + C21H35NO4SSi → S-benzilic-L-cysteic-NCA (22911-82-6)

Guidance literature:

With N,N-dimethyl-formamide; In dichloromethane; at 0 - 20 ℃;

DOI:10.1021/jo00212a042

Reference yield: 100.0%

bis(trichloromethyl) carbonate (32315-10-9) + S-Benzyl-L-Cys-Na-Salz → S-benzilic-L-cysteic-NCA (22911-82-6)

Guidance literature:

With 4-methyl-morpholine; In water; acetonitrile; at 20 ℃; Flow reactor;

DOI:10.1002/anie.201803549

upstream raw materials:

phosgene

S-benzyl-L-cysteine

benzyloxycarbonyl-S-benzylcysteine

oxalyl dichloride

Downstream raw materials:

S-benzyl-L-cysteinylglycine

(R)-4-benzylsulfanylmethyl-3-(2-nitro-phenylsulfanyl)-oxazolidine-2,5-dione

Refernces

• 1、 -. "Dendritic polypeptide-based nanocarriers for the delivery of therapeutic agents". Page/Page column 17; 18. . Retrieved 2018/04/25.
• 2、 Mobashery, Shahriar,Johnston, Michael. "A New Approach to the Preparation of N-Carboxy α-Amino Acid Anhydrides". . p. 2200 - 2202. Retrieved 2007/10/02.