(S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol methanesulfonate

Base Information

Chemical Name:(S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol methanesulfonate
CAS No.:1236354-27-0
Molecular Formula:CH₄O₃S*C₁₃H₁₁ClF₃NO
Molecular Weight:385.792
Hs Code.:

Synonyms:(S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol methanesulfonate

Suppliers and Price of (S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol methanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol methanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol methanesulfonate

There total 3 articles about (S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 75-75-2,98527-29-8
methanesulfonic acid

: 209414-27-7,927812-33-7,154598-58-0
(2S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol

: 1236354-27-0
(S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol methanesulfonate

Guidance literature:: In isopropyl alcohol; at 5 - 30 ℃; for 4h;

Reference yield:

: 6746-94-7
Cyclopropylacetylene

: 1236354-27-0
(S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol methanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1.1: diethylzinc; (1R,2S)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol / toluene; tetrahydrofuran / 1 h / 15 - 20 °C

1.2: 0 - 30 °C

1.3: 0.25 h / 20 °C

2.1: isopropyl alcohol / 4 h / 5 - 30 °C

diethylzinc; (1R,2S)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol; In tetrahydrofuran; isopropyl alcohol; toluene;

Reference yield:

: 154598-53-5
1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethanone

: 1236354-27-0
(S)-2-(2-amino-5-chlorophenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol methanesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1.1: diethylzinc; (1R,2S)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol / toluene; tetrahydrofuran / 1 h / 15 - 20 °C

1.2: 0 - 30 °C

1.3: 0.25 h / 20 °C

2.1: isopropyl alcohol / 4 h / 5 - 30 °C

diethylzinc; (1R,2S)-1-phenyl-2-(1-pyrrolidinyl)-1-propanol; In tetrahydrofuran; isopropyl alcohol; toluene;