3-Bromo-N-(tert-butyl)benzamide 97%

Base Information

• Chemical Name: 3-Bromo-N-(tert-butyl)benzamide 97%
• CAS No.: 42498-39-5
• Molecular Formula: C11H14 Br N O
• Molecular Weight: 256.142
• Hs Code.: 2924299090
• Mol file: 42498-39-5.mol

Synonyms:3-Bromo-N-(tert-butyl)benzamide 97%;3-bromo-N-tert-butylbenzamide;N-t-Butyl 3-bromobenzamide

Chemical Property of 3-Bromo-N-(tert-butyl)benzamide 97%

Chemical Property:

• Vapor Pressure: 7.89E-05mmHg at 25°C
• Refractive Index: 1.54
• Boiling Point: 341.7°Cat760mmHg
• PKA: 14.84±0.46(Predicted)
• Flash Point: 160.5°C
• PSA: 29.10000
• Density: 1.309g/cm³
• LogP: 3.36830
• Storage Temp.: 2-8°C

Purity/Quality:

98% ^*data from raw suppliers

N-t-Butyl3-bromobenzamide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

Useful:

Technology Process of 3-Bromo-N-(tert-butyl)benzamide 97%

There total 7 articles about 3-Bromo-N-(tert-butyl)benzamide 97% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

3-bromobenzoyl chloride (1711-09-7) + tert-butylamine (75-64-9) → 3-bromo-N-(tert-butyl)benzamide (42498-39-5)

Guidance literature:

In dichloromethane; at 0 - 20 ℃; for 4h;

Reference yield: 94.0%

3-cyanobromobenzene (6952-59-6) + benzoic acid tert-butyl ester (774-65-2) → 3-bromo-N-(tert-butyl)benzamide (42498-39-5)

Guidance literature:

With zinc perchlorate; In neat (no solvent); at 50 ℃; for 1h;

DOI:10.1007/s11696-018-0586-4

Reference yield: 81.0%

3-cyanobromobenzene (6952-59-6) + tert-butyl alcohol (75-65-0) → 3-bromo-N-(tert-butyl)benzamide (42498-39-5)

Guidance literature:

3-cyanobromobenzene; tert-butyl alcohol; for 13h; Inert atmosphere; Heating;

With water; Inert atmosphere;

DOI:10.1016/j.tetlet.2020.152553

upstream raw materials:

3-bromobenzoyl chloride

tert-butylamine

3-cyanobromobenzene

tert-butyl alcohol

Downstream raw materials:

N-tert-butyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide

N-t-Butyl-3-(3-chloro-5-methoxyphenoxy)-benzamid

Refernces

• 1、 Malviya, Bhanwar Kumar,Singh, Karandeep,Jaiswal, Pradeep K.,Karnatak, Manvika,Verma, Ved Prakash,Badsara, Satpal Singh,Sharma, Siddharth. "Catalyst-free synthesis of phenanthridinesviaelectrochemical coupling of 2-isocyanobiphenyls and amines". . p. 6367 - 6378. Retrieved 2021/04/16.
• 2、 Sutar, Suraj M.,Savanur, Hemantkumar M.,Kalkhambkar, Rajesh G.,Borosky, Gabriela L.,Aridoss, Gopalakrishnan,Laali, Kenneth K.. "Ionic liquid catalyzed Ritter reaction/Pd-catalyzed directed Ortho-arylation; facile access to diverse libraries of biaryl-amides from Aryl-nitriles". supporting information. . Retrieved 2020/10/30.