(S)-ethyl 3-(4-methoxyphenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate

Base Information

Chemical Name:(S)-ethyl 3-(4-methoxyphenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate
CAS No.:1198356-00-1
Molecular Formula:C₁₈H₂₇BO₅
Molecular Weight:334.22
Hs Code.:

Synonyms:(S)-ethyl 3-(4-methoxyphenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate

Suppliers and Price of (S)-ethyl 3-(4-methoxyphenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-ethyl 3-(4-methoxyphenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of (S)-ethyl 3-(4-methoxyphenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate

There total 4 articles about (S)-ethyl 3-(4-methoxyphenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 24393-56-4,51507-22-3,1929-30-2
ethyl p-methoxycinnamate

: 73183-34-3
bis(pinacol)diborane

: 1198356-00-1
(S)-ethyl 3-(4-methoxyphenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate

Guidance literature:: With Rh(Phebox-sb); sodium t-butanolate; In toluene; at 80 ℃; for 0.5h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1039/b915759j

Reference yield: 89.0%

: 24393-56-4
ethyl (E)-3-(4-methoxyphenyl)prop-2-enoate

: 73183-34-3
bis(pinacol)diborane

: 1198356-00-1
(S)-ethyl 3-(4-methoxyphenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate

Guidance literature:: With C₂₄H₃₅N₂O₇Rh; sodium t-butanolate; In toluene; at 80 ℃; for 0.5h; enantioselective reaction; Inert atmosphere;
DOI:10.1016/j.tet.2013.02.086

Reference yield:

: 24393-56-4
ethyl (E)-3-(4-methoxyphenyl)prop-2-enoate

: 73183-34-3
bis(pinacol)diborane

: (R)-ethyl 3-(4-methoxyphenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate

: 1198356-00-1
(S)-ethyl 3-(4-methoxyphenyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate

Guidance literature:: With C₂₂H₃₁N₂O₇Rh; sodium t-butanolate; In toluene; at 80 ℃; for 0.5h; Overall yield = 91 %; enantioselective reaction; Inert atmosphere;
DOI:10.1016/j.tet.2013.02.086