Technology Process of (+/)-diisobutylphosphine oxide
There total 1 articles about (+/)-diisobutylphosphine oxide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium hydroxide semihydrate; phosphorus; N-benzyl-N,N,N-triethylammonium chloride;
In
toluene;
at 60 - 62 ℃;
for 5h;
Inert atmosphere;
DOI:10.1016/j.mencom.2019.05.030
- Guidance literature:
-
With
tris-(dibenzylideneacetone)dipalladium(0); caesium carbonate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene;
In
1,4-dioxane;
at 80 ℃;
DOI:10.1039/c8sc04896g
- Guidance literature:
-
Multi-step reaction with 3 steps
1: caesium carbonate; tris-(dibenzylideneacetone)dipalladium(0); 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene / 1,4-dioxane / 80 °C
2: hydrogen; palladium on activated charcoal / ethanol
3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; dmap / dichloromethane
With
dmap; tris-(dibenzylideneacetone)dipalladium(0); palladium on activated charcoal; hydrogen; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene;
In
1,4-dioxane; ethanol; dichloromethane;
DOI:10.1039/c8sc04896g
