isobutyl hypophosphorous acid

Base Information

• Chemical Name: isobutyl hypophosphorous acid
• CAS No.: 54423-73-3
• Molecular Formula: C₄H₁₁O₂P
• Molecular Weight: 122.104
• Mol file: 54423-73-3.mol

Synonyms:isobutyl hypophosphorous acid

Chemical Property of isobutyl hypophosphorous acid

Chemical Property:

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Technology Process of isobutyl hypophosphorous acid

There total 2 articles about isobutyl hypophosphorous acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

2-methyl-propan-1-ol (78-83-1) → propylene glycol (57-55-6,63625-56-9) + isobutyl hypophosphorous acid (54423-73-3)

Guidance literature:

With hypophosphorous acid; methyloxirane; at 45 - 50 ℃; for 1h; or epichlorohydrin;

Reference yield: 7.0%

Isobutyl bromide (78-77-3) → isobutyl hypophosphorous acid (54423-73-3) + P(i-C4H9)3O (7682-87-3) + (+/)-diisobutylphosphine oxide (15924-55-7)

Guidance literature:

With potassium hydroxide semihydrate; phosphorus; N-benzyl-N,N,N-triethylammonium chloride; In toluene; at 60 - 62 ℃; for 5h; Inert atmosphere;

DOI:10.1016/j.mencom.2019.05.030

upstream raw materials:

2-methyl-propan-1-ol

Isobutyl bromide