3-(4-chlorobenzoyl)-2-<<(trifluoromethyl)carbonyl>amino>benzeneacetic acid, ethyl ester

Base Information

Chemical Name:3-(4-chlorobenzoyl)-2-<<(trifluoromethyl)carbonyl>amino>benzeneacetic acid, ethyl ester
CAS No.:126849-28-3
Molecular Formula:C₁₉H₁₅ClF₃NO₄
Molecular Weight:413.781
Hs Code.:

Synonyms:3-(4-chlorobenzoyl)-2-<<(trifluoromethyl)carbonyl>amino>benzeneacetic acid, ethyl ester

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Chemical Property of 3-(4-chlorobenzoyl)-2-<<(trifluoromethyl)carbonyl>amino>benzeneacetic acid, ethyl ester

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Technology Process of 3-(4-chlorobenzoyl)-2-<<(trifluoromethyl)carbonyl>amino>benzeneacetic acid, ethyl ester

There total 2 articles about 3-(4-chlorobenzoyl)-2-<<(trifluoromethyl)carbonyl>amino>benzeneacetic acid, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 61941-66-0
2-amino-3-(4-chlorobenzoyl)benzeneacetic acid,ethyl ester

: 407-25-0
trifluoroacetic anhydride

: 126849-28-3
3-(4-chlorobenzoyl)-2-<<(trifluoromethyl)carbonyl>amino>benzeneacetic acid, ethyl ester

Guidance literature:: In dichloromethane; for 0.25h; Ambient temperature;
DOI:10.1021/jm00170a039

Reference yield:

: 61941-62-6
2-amino-3-(4-chlorobenzoyl)benzeneacetic acid, sodium salt

: 126849-28-3
3-(4-chlorobenzoyl)-2-<<(trifluoromethyl)carbonyl>amino>benzeneacetic acid, ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / dimethylformamide / 2.5 h / Ambient temperature

2: 78 percent / CH₂Cl₂ / 0.25 h / Ambient temperature

In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm00170a039