1-azido-1-deoxy-4-O-methanesulphonyl-2,3,5-tri-O-benzyl-D-xylitol

Base Information

• Chemical Name: 1-azido-1-deoxy-4-O-methanesulphonyl-2,3,5-tri-O-benzyl-D-xylitol
• CAS No.: 100806-54-0
• Molecular Formula: C₂₇H₃₁N₃O₆S
• Molecular Weight: 525.626
• Mol file: 100806-54-0.mol

Synonyms:1-azido-1-deoxy-4-O-methanesulphonyl-2,3,5-tri-O-benzyl-D-xylitol

Chemical Property of 1-azido-1-deoxy-4-O-methanesulphonyl-2,3,5-tri-O-benzyl-D-xylitol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-azido-1-deoxy-4-O-methanesulphonyl-2,3,5-tri-O-benzyl-D-xylitol

There total 1 articles about 1-azido-1-deoxy-4-O-methanesulphonyl-2,3,5-tri-O-benzyl-D-xylitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

1,4-di-O-methanesulfonyl-2,3,5-tri-O-benzyl-D-xylitol (100806-53-9) → 1-azido-1-deoxy-4-O-methanesulphonyl-2,3,5-tri-O-benzyl-D-xylitol (100806-54-0)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide; at 50 ℃; for 12h;

DOI:10.1016/S0040-4020(01)88174-6

Reference yield:

1-azido-1-deoxy-4-O-methanesulphonyl-2,3,5-tri-O-benzyl-D-xylitol (100806-54-0) → (2S,3S,4S)-2-benzyloxymethyl-3,4-dibenzyloxy-pyrrolidin (100806-55-1)

Guidance literature:

With hydrogen; palladium; In ethanol;

DOI:10.1016/S0040-4039(00)98636-2

Reference yield:

1-azido-1-deoxy-4-O-methanesulphonyl-2,3,5-tri-O-benzyl-D-xylitol (100806-54-0) → (2S,3S,4S)-2-(hydroxymethyl)pyrrolidine-3,4-diol (52019-89-3,97058-12-3,98632-49-6,100937-51-7,100937-52-8,100937-53-9,105990-40-7,105990-41-8,105990-42-9,129568-47-4,186759-56-8,187339-50-0)

Guidance literature:

With hydrogen; palladium; Multistep reaction; 1.) ethanol, room temperature, 90 min, 2.) acetic acid, room temperature, 4 days;

DOI:10.1016/S0040-4020(01)88174-6

upstream raw materials:

1,4-di-O-methanesulfonyl-2,3,5-tri-O-benzyl-D-xylitol

Downstream raw materials:

(2S,3S,4S)-2-benzyloxymethyl-3,4-dibenzyloxy-pyrrolidin

(2S,3S,4S)-2-(hydroxymethyl)pyrrolidine-3,4-diol

1,4-dideoxy-1,4-imino-L-arabinitol hydrochloride