3-(4-Benzyloxy-phenyl)-isoxazole-5-carbaldehyde

Base Information

Chemical Name:3-(4-Benzyloxy-phenyl)-isoxazole-5-carbaldehyde
CAS No.:337355-81-4
Molecular Formula:C17H13 N O3
Molecular Weight:279.295
Hs Code.:2934999090
DSSTox Substance ID:DTXSID30473647
Nikkaji Number:J1.528.005K
Wikidata:Q82303167
Mol file:337355-81-4.mol

Synonyms:337355-81-4;3-(4-BENZYLOXY-PHENYL)-ISOXAZOLE-5-CARBALDEHYDE;3-(4-phenylmethoxyphenyl)-1,2-oxazole-5-carbaldehyde;3-(4-(benzyloxy)phenyl)isoxazole-5-carbaldehyde;3-(4-phenylmethoxyphenyl)-5-isoxazolecarboxaldehyde;SCHEMBL189438;DTXSID30473647;FHFSYUPEVSXYLG-UHFFFAOYSA-N;AB27246;FT-0744646;3-(4-benzyloxy-phenyl)-isoxazol-5-carbaldehyde;A821911

Suppliers and Price of 3-(4-Benzyloxy-phenyl)-isoxazole-5-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-(4-(Benzyloxy)phenyl)isoxazole-5-carbaldehyde 97%
1g
$ 1200.00

Total 7 raw suppliers

Chemical Property of 3-(4-Benzyloxy-phenyl)-isoxazole-5-carbaldehyde

Chemical Property:

PSA：52.33000
LogP:3.73310
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:279.08954328
Heavy Atom Count:21
Complexity:322

Purity/Quality:

99%, ^*data from raw suppliers

3-(4-(Benzyloxy)phenyl)isoxazole-5-carbaldehyde 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=CC=C(C=C2)C3=NOC(=C3)C=O

Technology Process of 3-(4-Benzyloxy-phenyl)-isoxazole-5-carbaldehyde

There total 3 articles about 3-(4-Benzyloxy-phenyl)-isoxazole-5-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 883749-85-7
[3-(4-benzyloxy-phenyl)-isoxazol-5-yl]-methanol

: 337355-81-4
3-(4-benzyloxy-phenyl)-isoxazol-5-carbaldehyde

Guidance literature:: With silica gel; pyridinium chlorochromate; In dichloromethane; for 5h;
DOI:10.1016/j.bmc.2004.06.011

Reference yield:

: 4397-53-9
p-benzyloxybenzaldehyde

: 337355-81-4
3-(4-benzyloxy-phenyl)-isoxazol-5-carbaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1.1: NH₂OH*HCl; Na₂CO₃ / ethanol; H₂O / 1 h / 60 °C

2.1: N-chlorosuccinimide; pyridine / tetrahydrofuran / 0.5 h / 60 °C

2.2: triethylamine / tetrahydrofuran / 2 h / 50 °C

3.1: pyridinium chlorochromate; silica gel / CH₂Cl₂ / 5 h

With pyridine; N-chloro-succinimide; hydroxylamine hydrochloride; silica gel; sodium carbonate; pyridinium chlorochromate; In tetrahydrofuran; ethanol; dichloromethane; water;
DOI:10.1016/j.bmc.2004.06.011

Reference yield:

: 76193-67-4
4-benzyloxybenzaldehyde oxime

: 337355-81-4
3-(4-benzyloxy-phenyl)-isoxazol-5-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: N-chlorosuccinimide; pyridine / tetrahydrofuran / 0.5 h / 60 °C

1.2: triethylamine / tetrahydrofuran / 2 h / 50 °C

2.1: pyridinium chlorochromate; silica gel / CH₂Cl₂ / 5 h

With pyridine; N-chloro-succinimide; silica gel; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmc.2004.06.011