[2-Methyl-4,5-bis(methoxymethoxy)phenyl]boronic acid

Base Information

Chemical Name:[2-Methyl-4,5-bis(methoxymethoxy)phenyl]boronic acid
CAS No.:532394-19-7
Molecular Formula:C₁₁H₁₇BO₆
Molecular Weight:256.063
Hs Code.:
DSSTox Substance ID:DTXSID101203907
Nikkaji Number:J1.871.719K

Synonyms:DTXSID101203907;[2-Methyl-4,5-bis(methoxymethoxy)phenyl]boronic acid;Boronic acid, [4,5-bis(methoxymethoxy)-2-methylphenyl]-;532394-19-7

Suppliers and Price of [2-Methyl-4,5-bis(methoxymethoxy)phenyl]boronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of [2-Methyl-4,5-bis(methoxymethoxy)phenyl]boronic acid

Chemical Property:

Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:256.1118184
Heavy Atom Count:18
Complexity:228

Purity/Quality:: 95%-98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:B(C1=CC(=C(C=C1C)OCOC)OCOC)(O)O

Technology Process of [2-Methyl-4,5-bis(methoxymethoxy)phenyl]boronic acid

There total 2 articles about [2-Methyl-4,5-bis(methoxymethoxy)phenyl]boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 532394-28-8
1-bromo-4,5-bis(methoxymethoxy)-2-methylbenzene

: 532394-19-7
C₁₁H₁₇BO₆

Guidance literature:: 1-bromo-4,5-bis(methoxymethoxy)-2-methylbenzene; With n-butyllithium; In tetrahydrofuran; at -78 - -40 ℃;

With Triisopropyl borate; In tetrahydrofuran; diethyl ether; at -78 - 20 ℃;
DOI:10.1016/S0040-4039(03)00072-8

Reference yield:

: 18863-72-4
4-bromo-5-methylbenzene-1,2-diol

: 532394-19-7
C₁₁H₁₇BO₆

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / NaH / dimethylformamide / 6 h / 0 °C

2: 95 percent / n-BuLi; (i-PrO)3B / tetrahydrofuran; hexane; diethyl ether / 4 h / -78 - 20 °C

With n-butyllithium; Triisopropyl borate; sodium hydride; In tetrahydrofuran; diethyl ether; hexane; N,N-dimethyl-formamide;
DOI:10.1016/j.tet.2004.05.017

Reference yield: 93.0%

: 532394-19-7
C₁₁H₁₇BO₆

: 532394-17-5
7-methoxy-2,2-dimethyl-5-(trifluoromethylsulfonyloxy)benzo[1,3]dioxin-4-one

: 709024-96-4
5-[4,5-bis(methoxymethoxy)-2-methylphenyl]-7-methoxy-2,2-dimethyl-4H-1,3-benzodioxin-4-one

Guidance literature:: With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium bromide; In 1,4-dioxane; at 100 ℃;
DOI:10.1016/S0040-4039(03)00072-8