(Z)-ethyl 7-(4-methoxyphenyl)-4H-pyrazolo[5,1-d][1,2,3,5]thiatriazin-4-ylidenecarbamate

Base Information

• Chemical Name: (Z)-ethyl 7-(4-methoxyphenyl)-4H-pyrazolo[5,1-d][1,2,3,5]thiatriazin-4-ylidenecarbamate
• CAS No.: 1448041-60-8
• Molecular Formula: C₁₄H₁₃N₅O₃S
• Molecular Weight: 331.355
• Mol file: 1448041-60-8.mol

Synonyms:(Z)-ethyl 7-(4-methoxyphenyl)-4H-pyrazolo[5,1-d][1,2,3,5]thiatriazin-4-ylidenecarbamate

Chemical Property of (Z)-ethyl 7-(4-methoxyphenyl)-4H-pyrazolo[5,1-d][1,2,3,5]thiatriazin-4-ylidenecarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-ethyl 7-(4-methoxyphenyl)-4H-pyrazolo[5,1-d][1,2,3,5]thiatriazin-4-ylidenecarbamate

There total 2 articles about (Z)-ethyl 7-(4-methoxyphenyl)-4H-pyrazolo[5,1-d][1,2,3,5]thiatriazin-4-ylidenecarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

3-diazo-5-(4-methoxyphenyl)-3H-pyrazole (1448041-62-0) + Ethoxycarbonyl isothiocyanate (16182-04-0) → (Z)-ethyl 7-(4-methoxyphenyl)-4H-pyrazolo[5,1-d][1,2,3,5]thiatriazin-4-ylidenecarbamate (1448041-60-8)

Guidance literature:

In ethyl acetate; at -10 - 20 ℃; Darkness;

DOI:10.1016/j.tet.2013.06.062

Reference yield:

5-amino-3-(4-methoxyphenyl)pyrazole (19541-95-8) → (Z)-ethyl 7-(4-methoxyphenyl)-4H-pyrazolo[5,1-d][1,2,3,5]thiatriazin-4-ylidenecarbamate (1448041-60-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium nitrite; hydrogenchloride / -5 °C

2: ethyl acetate / -10 - 20 °C / Darkness

With hydrogenchloride; sodium nitrite; In ethyl acetate;

DOI:10.1016/j.tet.2013.06.062

upstream raw materials:

3-diazo-5-(4-methoxyphenyl)-3H-pyrazole

Ethoxycarbonyl isothiocyanate

5-amino-3-(4-methoxyphenyl)pyrazole