2-(DIMETHYLVINYLSILYL)PYRIDINE

Base Information

• Chemical Name: 2-(DIMETHYLVINYLSILYL)PYRIDINE
• CAS No.: 321155-39-9
• Molecular Formula: C9H13 N Si
• Molecular Weight: 163.294
• Hs Code.: 2933399090
• European Community (EC) Number: 623-630-3
• Nikkaji Number: J1.456.979K
• Mol file: 321155-39-9.mol

Synonyms:Dimethyl(2-pyridinyl)(vinyl)silane;Dimethyl(2-pyridyl)vinylsilane

Chemical Property of 2-(DIMETHYLVINYLSILYL)PYRIDINE

Chemical Property:

• Vapor Pressure: 0.359mmHg at 25°C
• Refractive Index: n20/D 1.504
• Boiling Point: 205.4oC at 760 mmHg
• PKA: 5.49±0.12(Predicted)
• Flash Point: 78oC
• PSA: 12.89000
• Density: 0.9g/cm3
• LogP: 1.72220
• Storage Temp.: Refrigerator
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 163.081725953
• Heavy Atom Count: 11
• Complexity: 143

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-(Dimethylvinylsilyl)pyridine >97.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C[Si](C)(C=C)C1=CC=CC=N1
• Uses: Participates in a variety of C-C and C-X bond-forming processes including carbomagnesiation and borylation.1 Participates in a variety of C-C and C-X bond-forming processes including carbomagnesiation and borylation.

Technology Process of 2-(DIMETHYLVINYLSILYL)PYRIDINE

There total 1 articles about 2-(DIMETHYLVINYLSILYL)PYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

2-bromo-pyridine (109-04-6) + Chlorodimethylvinylsilane (1719-58-0) → dimethyl(2-pyridinyl)(vinyl)silane (321155-39-9)

Guidance literature:

2-bromo-pyridine; With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 1.5h;

Chlorodimethylvinylsilane; In diethyl ether; hexane; at -78 - 20 ℃; Further stages.;

DOI:10.1021/ja002582q

Reference yield: 99.0%

iodobenzene (591-50-4) + dimethyl(2-pyridinyl)(vinyl)silane (321155-39-9) → (E)-β-dimethyl(2-pyridyl)silyl-styrene (270588-96-0)

Guidance literature:

With trifuran-2-yl-phosphane; triethylamine; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In tetrahydrofuran; at 50 ℃; for 24h;

DOI:10.1021/ol048620i

Reference yield: 97.0%

para-iodoanisole (696-62-8) + dimethyl(2-pyridinyl)(vinyl)silane (321155-39-9) → (E)-β-(2-pyridyldimethylsilyl)-4-methoxystyrene (795311-52-3)

Guidance literature:

With trifuran-2-yl-phosphane; triethylamine; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In tetrahydrofuran; at 50 ℃;

DOI:10.1021/ol048620i

upstream raw materials:

2-bromo-pyridine

Chlorodimethylvinylsilane

Downstream raw materials:

(E)-β-dimethyl(2-pyridyl)silyl-styrene

(E)-β-(2-pyridyldimethylsilyl)-4-methylstyrene

(E)-1-dimethyl(2-pyridyl)silyl-2-phenyl-2-(2-thienyl)ethene

Refernces